Microbiome in postoperative delirium after cardiac surgery
51 fecal samples from adults in Beijing, China, undergoing elective cardiac surgery, comparing patients who developed postoperative delirium with matched non-delirium controls in a case-control design. machine-written summary
51 samples · 51 runs · CN · Age unknown · 2024 · 6.28 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 255 sample values (collection date, country, latitude, location locality, longitude) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 51 sample values (location site) · PMC13486744 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Surgical procedure studied before/after (bariatric surgery design observational_with_procedure · population other_disease · Elective on-pump cardiac surgery; pre- and post-operative fecal sampling
“317 adults undergoing elective on-pump cardiac surgery were enrolled” — abstract:42285959 (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
Schedule stated by the source: “Paired preoperative and postoperative fecal samples collected per patient (first postadmission bowel movement before antibiotics, and first postoperative bowel movement), with POD outcome ascertained ”; stated follow-up 7 d.
Genera, mean relative abundance over 48 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 51 | 100% | ||||
| country | 51 | 100% | 51 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 51 | 100% | 51 | |||
| detailed_location | 51 | 100% | ||||
| latitude | 51 | 100% | 51 | |||
| location_locality | 51 | 100% | 51 | |||
| location_site | 51 | 100% | 51 | |||
| longitude | 51 | 100% | 51 |
- Preoperative gut microbial network alterations and BCAA-Related metabolic disturbance in postoperative delirium after cardiac surgery: a prospective matched multi-omic study. 2026 PMID 42285959 PMC13486744 own_data
Archive description
Performing gut microbiota sequencing utilizing fecal samples.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.53. Assay shotgun_dna.
- host study.description · “gut microbiota sequencing utilizing fecal samples”
- body site study.description · “fecal samples”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN43882348 | collection_date | 2022-09-01 | R1 | 0.90 | biosample.attribute:collection_date | 2022-09-01 |
| SAMN43882348 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Beijing |
| SAMN43882348 | latitude | 39.5600 | R1 | 0.90 | biosample.attribute:lat_lon | 39.56 N 116.20 E |
| SAMN43882348 | location_locality | Beijing | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Beijing |
| SAMN43882348 | location_site | Fuwai Hospital | R3 | 0.70 | paper.fulltext.methods | conducted at Fuwai Hospital, Beijing, China |
| SAMN43882348 | longitude | 116.2000 | R1 | 0.90 | biosample.attribute:lat_lon | 39.56 N 116.20 E |
Sequencing
51 runs over 51 samples · mean 6.19 Gbp per run (median 6.28 Gbp, total 315.78 Gbp; 51 runs with a base count) · layout PAIRED 51 · platform ILLUMINA 51 · models Illumina NovaSeq 6000 (51) · 94% of runs with a Sandpiper profile · first public 2024-09-24
Help complete this project
2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata
Downloads
PRJNA1164032.csv.gz (2.2 KB) · parquet (71.3 KB) — all 51 samples, every field with route and confidence · PRJNA1164032_determinations.csv.gz (2.5 KB) — 306 evidence rows