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PRJNA1165922 SRP535656

Xylo-oligosaccharide, gut microbiota, pregnancy, GDM risk

Modulation of xylo-oligosaccharide on gut microbiota in pregnant women with high risk factors for gestational diabetes mellitus

100 gut microbiome samples from pregnant women with high risk factors for gestational diabetes mellitus, studying the effect of a prebiotic/fibre (xylo-oligosaccharide) intervention; location not reported. machine-written summary

100 samples · 100 runs · Adult · 2024 · 14.26 Gbp / sample

Sources
✓Sequence archive 300–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive300 sample values (collection date, subject id, timepoint)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Prebiotic / dietary fibre supplement design single_arm_before_after · population pregnancy_postpartum · Xylo-oligosaccharide supplementation in pregnant women at GDM risk

“Modulation of xylo-oligosaccharide on gut microbiota” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
Age
adult100
Body site
primary100
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 100 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 14.26 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

50 of 50 people sampled more than once (100 samples; median 2, up to 2 per person).

How longitudinal and relatedness information is derived

Community composition
Prevotella 12.1%Phocaeicola 10.9%Faecalibacterium 7.9%Bacteroides 6.8%Roseburia 5.6%Blautia_A 3.7%Bifidobacterium 2.6%Alistipes 2.5%Lachnospira 2.4%Megamonas 2.4%Dialister 2.1%Ruminococcoides 2.1%not assigned to a genus 2.8%other genera 36.3%

Genera, mean relative abundance over 90 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category100 100%
country0 0%
health_condition0 0%
subject_id100 100%100
collection_date100 100%100
timepoint_label100 100%100
Details
Archive description

Modulation of xylo-oligosaccharide on gut microbiota in pregnant women with high risk factors for gestational diabetes mellitus

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_unknown_no_evidence”
  • body site study.title · “of xylo-oligosaccharide on gut microbiota in pregnant”
  • body site study.description · “of xylo-oligosaccharide on gut microbiota in pregnant”
  • life stage study.title · “gut microbiota in pregnant women with high risk”
  • life stage study.description · “gut microbiota in pregnant women with high risk”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN43948966collection_date2019R10.90biosample.attribute:collection_date2019
SAMN43948966subject_idGDMC102R10.70sample.name_rule:alias+TITLEGDMC10201 (Control-pre)
SAMN43948966timepoint_labelpreR10.85biosample.attribute:samp_sizeControl-pre
Sequencing

100 runs over 100 samples · mean 14.07 Gbp per run (median 14.26 Gbp, total 1,407.42 Gbp; 100 runs with a base count) · layout PAIRED 100 · platform ILLUMINA 100 · models Illumina HiSeq X (100) · 90% of runs with a Sandpiper profile · first public 2024-10-22 – 2024-12-01

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: country, health_condition. Share metadata

Downloads

PRJNA1165922.csv.gz (3.3 KB) · parquet (72.8 KB) — all 100 samples, every field with route and confidence · PRJNA1165922_determinations.csv.gz (3.2 KB) — 300 evidence rows

Samples (100 · every field this project has values for · hover a cell for its source)
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