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PRJNA1170939 SRP545247

Fungal isolates from GI tract of organ donors, case-control

Fungi in GI of Organ Donors

26 samples from the gastrointestinal tract of adult brain-dead and donation-after-circulatory-death organ donors, comparing fungal presence and load between donor types; case-control design. machine-written summary

26 samples · 26 runs · US · Age unknown · 2025 · 1.46 Gbp / sample

Sources
✓Sequence archive 182○Abstract / description✓Full text 26○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive182 sample values (collection date, country, latitude, location locality, location region, longitude, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text26 sample values (location site) · PMC12323666
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult26
Country
US26
Body site
primary26
Collected 2021–2024
2021: 11 samples2022: 3 samples2023: 11 samples2024: 1 samples20212024
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 26 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.46 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

6 of 9 people sampled more than once (23 samples; median 4, up to 5 per person).

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category26 100%
country26 100%26
health_condition0 0%
subject_id26 100%26
collection_date26 100%26
detailed_location26 100%
latitude26 100%26
location_locality26 100%26
location_region26 100%26
location_site26 100%26
longitude26 100%26
Papers (1)
  • Increased fungal burden in the gastrointestinal tract of brain-dead organ donors. 2025 PMID 40530808 PMC12323666 own_data
Details
Archive description

Fungal isolates from GI of brain-dead organ donors and donation after circulatory death donors (DCD).

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.55. Assay shotgun_dna.

  • host study.title · “Fungi in GI of Organ Donors”
  • body site study.description · “Fungal isolates from GI of brain-dead”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN44115006collection_date2021-02R10.90biosample.attribute:collection_date2021-02
SAMN44115006countryUSR10.90sample.attr.geo_loc_nameUSA: Houston, TX
SAMN44115006latitude29.7100R10.90biosample.attribute:lat_lon29.71 N 95.40 W
SAMN44115006location_localityHoustonR10.85biosample.attribute:geo_loc_nameUSA: Houston, TX
SAMN44115006location_regionTexasR10.75biosample.attribute:geo_loc_nameUSA: Houston, TX
SAMN44115006location_siteTexas Medical CenterR30.70paper.fulltext.methodslocated in the Texas Medical Center
SAMN44115006longitude-95.4000R10.90biosample.attribute:lat_lon29.71 N 95.40 W
SAMN44115006subject_idDonor 1R10.85biosample.attribute:env_mediumDonor 1
Sequencing

26 runs over 26 samples · mean 1.62 Gbp per run (median 1.46 Gbp, total 42.17 Gbp; 26 runs with a base count) · layout PAIRED 26 · platform ILLUMINA 26 · models Illumina NovaSeq X Plus (26) · 100% of runs with a Sandpiper profile · first public 2025-03-30

Authors (14)

Nachman EJ first · Ardis CK · B Ardis AK · Nieto J · Bresson MM · Robertson CM · Seale MN · Villafuerte NM · Lyu Z · Preisner EC · Danhof HA · Di Rienzi SC · T Becker Y · Britton RA last

Downloads

PRJNA1170939.csv.gz (1.6 KB) · parquet (70.9 KB) — all 26 samples, every field with route and confidence · PRJNA1170939_determinations.csv.gz (2.0 KB) — 208 evidence rows

Samples (26 · every field this project has values for · hover a cell for its source)
Loading the sample table…