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PRJNA1173388 SRP538819

Gut metagenomes in IBD case-control cohort, Singapore

Metagenomes from an inflammatory bowel disease cohort

Shotgun metagenomic data from 82 gut microbiome samples collected in Singapore, comparing Crohn's disease, ulcerative colitis, and healthy controls in a case-control design. machine-written summary

82 samples · 82 runs · SG · Age unknown · 2025 · 6.57 Gbp / sample

Sources
✓Sequence archive 656–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive656 sample values (collection date, country, health condition, health condition detail, latitude, location locality, longitude, subject id)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown82
Condition
crohns_disease31
ulcerative_colitis29
healthy_control22
Country
SG82
Body site
primary82
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 76 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 6 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.57 Gbp per sample0130Gbp
Community composition
Bacteroides 12.1%Phocaeicola 9.7%Bifidobacterium 7.0%Prevotella 5.1%Faecalibacterium 4.8%Blautia_A 4.8%Roseburia 3.1%Alistipes 2.6%Streptococcus 2.5%Escherichia 2.1%Collinsella 1.9%Lachnospira 1.7%not assigned to a genus 3.8%other genera 38.8%

Genera, mean relative abundance over 81 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country82 100%82
health_condition82 100%82
subject_id82 100%82
collection_date82 100%82
detailed_location82 100%
health_condition_detail82 100%82
latitude82 100%82
location_locality82 100%82
longitude82 100%82
Details
Archive description

This study aimed to characterize the taxonomic and functional differences in the gut microbiome of Crohn's disease, ulcerative colitis, and healthy controls using shotgun metagenomic sequencing.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.82. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • host run.scientific_name · “human gut metagenome”
  • body site study.description · “gut microbiome of Crohn's disease”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN44303949collection_date2023R10.90biosample.attribute:collection_date2023
SAMN44303949countrySGR10.90sample.attr.geo_loc_nameSingapore
SAMN44303949health_conditioncrohns_diseaseR10.85biosample.attribute:descriptionCrohn's disease
SAMN44303949health_condition_detailCrohn's diseaseR10.85biosample.attribute:descriptionCrohn's disease
SAMN44303949latitude1.3521R10.90biosample.attribute:lat_lon1.3521 N 103.8198 E
SAMN44303949location_localitySingaporeR10.85biosample.attribute:geo_loc_nameSingapore
SAMN44303949longitude103.8198R10.90biosample.attribute:lat_lon1.3521 N 103.8198 E
SAMN44303949subject_idsubject 1R10.85biosample.attribute:source_material_idsubject 1
Sequencing

82 runs over 82 samples · mean 6.57 Gbp per run (median 6.57 Gbp, total 538.95 Gbp; 82 runs with a base count) · layout PAIRED 67, SINGLE 15 · platform ILLUMINA 82 · models Illumina NovaSeq 6000 (82) · 99% of runs with a Sandpiper profile · first public 2025-11-23

Authors (0)

No author record.

Downloads

PRJNA1173388.csv.gz (3.1 KB) · parquet (73.8 KB) — all 82 samples, every field with route and confidence · PRJNA1173388_determinations.csv.gz (4.8 KB) — 656 evidence rows

Samples (82 · every field this project has values for · hover a cell for its source)
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