Fecal transplant trial in anorexia nervosa, Copenhagen
49 gut microbiome samples from adult women with anorexia nervosa in Copenhagen, Denmark, in an open-label feasibility trial of fecal microbiota transplantation from healthy donors. machine-written summary
49 samples · 49 runs · DK · Age unknown · 2025 · 17.57 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 322 sample values (collection date, country, health condition, intervention, location locality, sex, subject id, timepoint) |
| ✓ Abstract / description | 49 sample values (health condition detail) |
| ✓ Full text | 49 sample values (location site) · PMC12913639 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Faecal microbiota transplantation design single_arm_before_after · population other_disease · Single FMT from healthy donors, oral capsules or rectal enema, in AN
“FMT was administered either orally via capsules or as rectal enema” — abstract:41535289 (study level; per-sample arms are in the intervention column below)
longitudinalFMT donor → recipient — not resolved
18 of 18 people sampled more than once (36 samples; median 2, up to 2 per person) · follow-up median 7 d (max 7 d) · median interval between samples 7 d (time from timepoint labels). Schedule stated by the source: “stool/blood collected pre-FMT (baseline, w0) and one week post-FMT (w1)” (time origin: transplant); stated follow-up 7 d.
Each row is one person (18 shown); dots are samples at days since that person's first sample.
18 anorexia nervosa FMT recipients (pre/post) and 13 donations from 2 donors; donor-recipient link not deposited.
Genera, mean relative abundance over 45 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 49 | 100% | ||||
| country | 49 | 100% | 49 | |||
| health_condition | 49 | 100% | 49 | |||
| subject_id | 36 | 73% | 36 | |||
| collection_date | 49 | 100% | 49 | |||
| detailed_location | 49 | 100% | ||||
| health_condition_detail | 49 | 100% | 49 | |||
| location_locality | 49 | 100% | 49 | |||
| location_site | 49 | 100% | 49 | |||
| sex | 36 | 73% | 36 | |||
| timepoint_label | 36 | 73% | 36 | |||
| intervention | 18 | 37% | 18 |
- Impact of a single fecal microbiome transplantation in adult women with anorexia nervosa: an open-label feasibility pilot trial. 2026 PMID 41535289 PMC12913639 own_data
Archive description
This study was aimed at investigating the extent to which gut microbiome of patients with Anorexia Nervosa shifted upon fecal microbiome transplantation received from healthy donors. Microbiome taxonomical alterations as well as potential changes in functional profile of the gut microbome of patients were investigated
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host run.scientific_name · “human gut metagenome”
- body site study.description · “gut microbiome of patients with Anorexia Nervosa”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN44656738 | collection_date | 2024-01-01 | R1 | 0.90 | biosample.attribute:collection_date | 2024-01-01 |
| SAMN44656738 | country | DK | R1 | 0.90 | sample.attr.geo_loc_name | Denmark:Copenhagen |
| SAMN44656738 | health_condition | neurological_psychiatric | R1 | 0.70 | sample.name_rule:alias | A03_EKDN240003400-1A_222T7HLT4_L6 |
| SAMN44656738 | health_condition_detail | Anorexia nervosa | R4 | 0.50 | paper.abstract | Adult female participants diagnosed with AN |
| SAMN44656756 | intervention | fmt | R1 | 0.70 | sample.name_rule:alias | B03 |
| SAMN44656738 | location_locality | Copenhagen | R1 | 0.85 | biosample.attribute:geo_loc_name | Denmark:Copenhagen |
| SAMN44656738 | location_site | Copenhagen University Hospital Hvidovre | R3 | 0.70 | paper.fulltext.methods | Copenhagen University Hospital Hvidovre (CUHH) |
| SAMN44656738 | sex | female | R1 | 0.70 | sample.name_rule:alias | A03_EKDN240003400-1A_222T7HLT4_L6 |
| SAMN44656738 | subject_id | P03 | R1 | 0.70 | sample.name_rule:alias | A03_EKDN240003400-1A_222T7HLT4_L6 |
| SAMN44656738 | timepoint_label | baseline | R1 | 0.70 | sample.name_rule:alias | A03_EKDN240003400-1A_222T7HLT4_L6 |
Sequencing
49 runs over 49 samples · mean 17.91 Gbp per run (median 17.57 Gbp, total 877.63 Gbp; 49 runs with a base count) · layout SINGLE 49 · platform ILLUMINA 49 · models Illumina NovaSeq X Plus (49) · 92% of runs with a Sandpiper profile · first public 2025-01-29
Authors (12)
Panah FM first · Støving RK · Sjögren M · Micali N · Maschek S · Reis KD · Mirsepasi-Lauridsen HC · Petersen AM · Nielsen DS · Helms M · Rasmussen MA · Barfod KK last
Downloads
PRJNA1184021.csv.gz (2.3 KB) · parquet (72.4 KB) — all 49 samples, every field with route and confidence · PRJNA1184021_determinations.csv.gz (3.9 KB) — 420 evidence rows