Metagenomes in Crohn's disease & physical activity, Hangzhou
90 fecal metagenome samples from Crohn's disease patients and healthy volunteers in Hangzhou, China, examining associations between physical activity and gut microbiota in a cross-sectional design. machine-written summary
90 samples · 90 runs · CN · Adult · 2025 · 5.76 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 630 sample values (age, collection date, country, health condition, health condition detail, location locality, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 180 sample values (location region, subject id) · PMC12323882 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 89 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 90 | 100% | ||||
| country | 90 | 100% | 90 | |||
| health_condition | 90 | 100% | 90 | |||
| subject_id | 90 | 100% | 90 | |||
| age_at_collection_days | 90 | 100% | 90 | |||
| collection_date | 90 | 100% | 90 | |||
| detailed_location | 90 | 100% | ||||
| health_condition_detail | 90 | 100% | 90 | |||
| location_locality | 90 | 100% | 90 | |||
| location_region | 90 | 100% | 90 | |||
| sex | 90 | 100% | 90 |
- Association of Recreational Physical Activity with Gut Microbiota Diversity and Composition, and Symptom Burden in Crohn's Disease: A Cross-Sectional Study. 2025 PMID 40765991 PMC12323882 own_data
Archive description
We collected fecal samples from Crohn's disease patients (n=52) and healthy volunteers (n=38) for metagenomic analysis to explore the impact of physical activity(patient self-report) on the microbiota of Crohn's disease patients.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “fecal samples from Crohn's disease patients”
- life stage study.description · “physical activity(patient self-report)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN44666788 | age_at_collection_days | 9861.8 | R1 | 0.70 | sample.attr.age | 27 |
| SAMN44666788 | collection_date | 2024-02-25 | R1 | 0.90 | biosample.attribute:collection_date | 2024-02-25T17:53:03Z |
| SAMN44666788 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:Hangzhou |
| SAMN44666788 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:isolate | isolate: Healthy Volunteers |
| SAMN44666788 | health_condition_detail | Healthy Volunteers | R1 | 0.85 | biosample.attribute:isolate | isolate: Healthy Volunteers |
| SAMN44666788 | location_locality | Hangzhou | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Hangzhou |
| SAMN44666788 | location_region | Zhejiang | R3 | 0.70 | paper.fulltext.methods | conducted at two Chinese IBD centers: Zhejiang Provincial Hospital |
| SAMN44666788 | sex | female | R1 | 0.90 | sample.attr.sex | female |
| SAMN44666788 | subject_id | SAMN44666788 | R3 | 0.70 | design.one_sample_per_subject:fulltext | fecal metagenomic data from 52 patients with CD ... along with 38 healthy control (HC) |
Sequencing
90 runs over 90 samples · mean 5.75 Gbp per run (median 5.76 Gbp, total 517.70 Gbp; 90 runs with a base count) · layout PAIRED 90 · platform ILLUMINA 90 · models Illumina NovaSeq 6000 (90) · 99% of runs with a Sandpiper profile · first public 2025-08-26
Downloads
PRJNA1184213.csv.gz (3.6 KB) · parquet (74.8 KB) — all 90 samples, every field with route and confidence · PRJNA1184213_determinations.csv.gz (6.7 KB) — 810 evidence rows