Fecal metagenomics in CRC, adenoma and healthy controls
Case-control study of 245 fecal metagenome samples from adults with colorectal cancer (100), colorectal adenoma (60), or healthy controls (85), examining gut microbiota linked to CRC tumorigenesis. machine-written summary
245 samples · 245 runs · CN · Adult · 2026 · 12.88 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 980 sample values (country, health condition, health condition detail, location locality) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC13285141 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 245 | 100% | ||||
| country | 245 | 100% | 245 | |||
| health_condition | 245 | 100% | 245 | |||
| subject_id | 0 | 0% | ||||
| detailed_location | 245 | 100% | ||||
| health_condition_detail | 245 | 100% | 245 | |||
| location_locality | 245 | 100% | 245 |
- Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP-Mediated Invasion Activates Ras Signaling and Destabilizes p53. 2026 PMID 41944309 PMC13285141 own_data
Archive description
Microbial DNA extracted from fecal sample from CRC patients, adenoma patients and healthy subjects.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “DNA extracted from stool samples of CRC,”
- body site study.description · “DNA extracted from fecal sample from CRC”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN45230396 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Wuhan |
| SAMN45230396 | health_condition | healthy_control | R1 | 0.80 | biosample_attr | control |
| SAMN45230396 | health_condition_detail | control | R1 | 0.90 | sample.attr.host_disease | control |
| SAMN45230396 | location_locality | Wuhan | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Wuhan |
Sequencing
245 runs over 245 samples · mean 13.01 Gbp per run (median 12.88 Gbp, total 3,188.19 Gbp; 245 runs with a base count) · layout PAIRED 245 · platform ILLUMINA 245 · models Illumina NovaSeq 6000 (245) · 0% of runs with a Sandpiper profile · first public 2026-05-24
Downloads
PRJNA1195392.csv.gz (6.1 KB) · parquet (77.9 KB) — all 245 samples, every field with route and confidence · PRJNA1195392_determinations.csv.gz (4.6 KB) — 980 evidence rows