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PRJNA1195614 SRP550453

Virome in gastric cancer patients & healthy controls, China

blood, upper respiratory tract, and gut metagenome

Viral metagenomic sequencing of 148 samples (blood and feces) from gastric cancer patients and healthy controls in Taizhou, China. Case-control study characterizing virome composition and identifying viral biomarkers associated with gastric cancer onset and metastasis. machine-written summary

148 samples · 148 runs · CN · Age unknown · 2025 · 2.84 Gbp / sample

Sources
✓Sequence archive 888✓Abstract / description 148–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive888 sample values (collection date, country, latitude, location locality, location region, longitude)
✓ Abstract / description148 sample values (health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown148
Country
CN148
Body site
excluded96
primary52
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 1 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 3 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 28 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 49 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 51 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 15 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.84 Gbp per sample0130Gbp
Community composition
Prevotella 22.7%Phocaeicola 6.9%Bacteroides 6.1%Faecalibacterium 3.5%Ruminococcus_C 3.1%CAG-302 2.8%Angelakisella 2.8%Romboutsia 1.7%CAG-611 1.6%Intestinibacter 1.5%CAG-217 1.4%Sarcina 1.3%not assigned to a genus 32.3%other genera 12.2%

Genera, mean relative abundance over 50 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country148 100%148
health_condition0 0%
subject_id0 0%
collection_date148 100%148
detailed_location148 100%
health_condition_detail148 100%148
latitude148 100%148
location_locality148 100%148
location_region148 100%148
longitude148 100%148
Papers (1)
  • Blood and gut virome remodeling in gastric cancer: Anellovirus expansion and novel virus discovery. 2026 PMID 42586263 PMC13556328 unsure
Details
Archive description

the goal of this study is to reveal the composition of the virome in different parts of the body of lung cancer patients and to compare the differences in virome composition between lung cancer patients and healthy individuals. collection date:January 2022 to January 2024.

How this project entered the registry

Classified as human gut / stool / lower respiratory / blood / tissue / internal fluids / nasal / nasopharyngeal shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.57. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “blood, upper respiratory tract, and gut metagenome”
  • body site sample.attr.isolation_source · “throat swab (n=36/148)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN45223791collection_date2024-01-31R10.90biosample.attribute:collection_date2024-01-31T08:01:22Z
SAMN45223791countryCNR10.90sample.attr.geo_loc_nameChina:Jiangsu,Taizhou
SAMN45223791health_condition_detailmixed_case_control: ENA describes lung cancer patients; linked paper (PMID 42586263) describes gastric cancer patients (R40.40study.descriptionlung cancer patients and healthy individuals
SAMN45223791latitude32.4849R10.90biosample.attribute:lat_lon32.484882 N 119.915176 E
SAMN45223791location_localityTaizhouR10.85biosample.attribute:geo_loc_nameChina:Jiangsu,Taizhou
SAMN45223791location_regionJiangsuR10.85biosample.attribute:geo_loc_nameChina:Jiangsu,Taizhou
SAMN45223791longitude119.9152R10.90biosample.attribute:lat_lon32.484882 N 119.915176 E
Sequencing

148 runs over 148 samples · mean 3.66 Gbp per run (median 2.84 Gbp, total 541.53 Gbp; 148 runs with a base count) · layout PAIRED 148 · platform ILLUMINA 148 · models Illumina NovaSeq 6000 (148) · 95% of runs with a Sandpiper profile · first public 2025-05-04

Authors (11)

Zhou Y first · Guo Q · Zhao X · Zhang W · Zhang H · Huang S · He Z · Xie Y · Gu J · Pan S · Li W last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA1195614.csv.gz (4.5 KB) · parquet (75.9 KB) — all 148 samples, every field with route and confidence · PRJNA1195614_determinations.csv.gz (8.0 KB) — 1,036 evidence rows

Samples (148 · every field this project has values for · hover a cell for its source)
Loading the sample table…