Gut metagenomes, CRC/adenoma case-control, Weifang, China
173 stool metagenome samples from Weifang, China, comparing healthy individuals, adenoma patients, and colorectal cancer patients in a case-control design, as part of a larger multi-cohort CRC detection study. machine-written summary
173 samples · 173 runs · CN · Age unknown · 2025 · 12.02 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,038 sample values (collection date, country, latitude, location locality, location region, longitude) |
| ✓ Abstract / description | 2 sample values (health condition detail) |
| ○ Full text | read; no usable statement or table · PMC12107961, PMC13381771 |
| ✓ Supplementary tables | 684 sample values (age, health condition, health condition detail, sex) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 171 | 99% | ||||
| country | 173 | 100% | 173 | |||
| health_condition | 171 | 99% | 171 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 173 | 100% | 173 | |||
| detailed_location | 173 | 100% | ||||
| health_condition_detail | 173 | 100% | 171 | 2 | ||
| latitude | 173 | 100% | 173 | |||
| location_locality | 173 | 100% | 173 | |||
| location_region | 173 | 100% | 173 | |||
| longitude | 173 | 100% | 173 | |||
| age_at_collection_days | 171 | 99% | 171 | |||
| sex | 171 | 99% | 171 |
- TaxaCal: enhancing species-level profiling accuracy of 16S amplicon data. 2025 PMID 40419960 PMC12107961 unsure
- Instance-based transfer learning enables cross-cohort early detection of colorectal cancer. 2026 PMID 42106361 PMC13381771 unsure
Archive description
The goal is to investigate changes in the intestinal microbial community in healthy individuals, patients with adenoma, and patients with colorectal cancer by analyzing stool samples.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host study.title · “Human gut metagenome”
- body site study.description · “by analyzing stool samples”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN45852858 | age_at_collection_days | 21184.0 | R2 | 0.80 | paper.supp.12859_2025_6156_MOESM2_ESM.xlsx[Table S1!Age(years)] | Age(years): 58 |
| SAMN45852858 | collection_date | 2021-12/2022-12 | R1 | 0.90 | biosample.attribute:collection_date | 2021-12/2022-12 |
| SAMN45852858 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: WeiFang |
| SAMN45852858 | health_condition | healthy_control | R2 | 0.80 | paper.supp.12859_2025_6156_MOESM2_ESM.xlsx[Table S1!Diagnosis] | Diagnosis: healthy |
| SAMN45852858 | health_condition_detail | healthy | R2 | 0.80 | paper.supp.12859_2025_6156_MOESM2_ESM.xlsx[Table S1!Diagnosis] | Diagnosis: healthy |
| SAMN45852949 | health_condition_detail | mixed_case_control: healthy individuals vs adenoma patients vs colorectal cancer patients | R4 | 0.50 | study.description | healthy individuals, patients with adenoma, and patients with colorectal cancer |
| SAMN45852858 | latitude | 36.7066 | R1 | 0.90 | biosample.attribute:lat_lon | 36.7066306 N 119.1268375 E |
| SAMN45852858 | location_locality | Weifang | R1 | 0.85 | biosample.attribute:geo_loc_name | China: WeiFang |
| SAMN45852858 | location_region | Shandong Sheng | R1 | 0.60 | biosample.attribute:lat_lon | 36.7066306 N 119.1268375 E |
| SAMN45852858 | longitude | 119.1268 | R1 | 0.90 | biosample.attribute:lat_lon | 36.7066306 N 119.1268375 E |
| SAMN45852858 | sex | male | R2 | 0.80 | paper.supp.12859_2025_6156_MOESM2_ESM.xlsx[Table S1!Gender] | Gender: M |
Sequencing
173 runs over 173 samples · mean 11.83 Gbp per run (median 12.02 Gbp, total 2,046.74 Gbp; 173 runs with a base count) · layout PAIRED 173 · platform DNBSEQ 173 · models DNBSEQ-T7 (173) · 0% of runs with a Sandpiper profile · first public 2025-04-27
Authors (10)
Shen Q first · Fan X · Sun Y · Gao H · Su X last · Wu S · Wu Z · Zhu W · Xing J · Zhao J
Downloads
PRJNA1198725.csv.gz (5.4 KB) · parquet (77.6 KB) — all 173 samples, every field with route and confidence · PRJNA1198725_determinations.csv.gz (13.6 KB) — 1,724 evidence rows