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PRJNA1199203 SRP551975

Faecal microbiome in IBS, cross-sectional, UK

Microbiome assessment of human patients with IBS

109 faecal samples from volunteers in the United Kingdom, comparing healthy and unhealthy (IBS) individuals in a cross-sectional design. machine-written summary

109 samples · 109 runs · GB · Age unknown · 2025 · 1.34 Gbp / sample

Sources
✓Sequence archive 804○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive804 sample values (collection date, country, health condition, health condition detail, latitude, longitude, subject id, timepoint)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown109
Condition
healthy_control39
ibs36
Country
GB109
Body site
primary109
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 2 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 2 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 32 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 65 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 8 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.34 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

26 of 30 people sampled more than once (105 samples; median 4, up to 6 per person).

How longitudinal and relatedness information is derived

Community composition
Faecalibacterium 6.9%Roseburia 6.6%Ruminococcoides 3.9%Gemmiger 3.5%Bacteroides 3.3%Blautia_A 3.2%Akkermansia 3.1%Bifidobacterium 2.8%Phocaeicola 2.6%Vescimonas 2.5%Prevotella 1.9%Alistipes 1.8%not assigned to a genus 12.5%other genera 45.1%

Genera, mean relative abundance over 106 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country109 100%109
health_condition75 69%75
subject_id109 100%109
collection_date109 100%109
latitude109 100%109
longitude109 100%109
timepoint_label109 100%109
health_condition_detail75 69%75
Details
Archive description

Comparison of faecal microbiome of healthy and unhealthy volunteers.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.80. Assay shotgun_dna.

  • host study.title · “human patients with IBS”
  • host run.host_tax_id · “9606”
  • body site study.description · “faecal microbiome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN45868320collection_date2017-08-01R10.90biosample.attribute:collection_date2017-08-01
SAMN45868320countryGBR10.90sample.attr.geo_loc_nameUnited Kingdom
SAMN45868336health_conditionhealthy_controlR10.70sample.name_rule:sample_aliasL-HV-11_S2
SAMN45868336health_condition_detailhealthy_control (decoded from sample name L-HV-11_S2)R10.70sample.name_rule:sample_aliasL-HV-11_S2
SAMN45868320latitude55.3781R10.90biosample.attribute:lat_lon55.3781 N 3.4360 W
SAMN45868320longitude-3.4360R10.90biosample.attribute:lat_lon55.3781 N 3.4360 W
SAMN45868320subject_id10R10.70sample.name_rule:sample_aliasL-FC-10_S17
SAMN45868320timepoint_labelLR10.70sample.name_rule:sample_aliasL-FC-10_S17
Sequencing

109 runs over 109 samples · mean 1.46 Gbp per run (median 1.34 Gbp, total 158.78 Gbp; 109 runs with a base count) · layout PAIRED 109 · platform ILLUMINA 109 · models Illumina NovaSeq X Plus (109) · 97% of runs with a Sandpiper profile · first public 2025-03-12 – 2025-03-23

Authors (0)

No author record.

Downloads

PRJNA1199203.csv.gz (4.0 KB) · parquet (74.9 KB) — all 109 samples, every field with route and confidence · PRJNA1199203_determinations.csv.gz (6.3 KB) — 804 evidence rows

Samples (109 · every field this project has values for · hover a cell for its source)
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