CRC tumor microbiome and immune transcriptomics, Suzhou, China
62 samples from colorectal cancer patients in Suzhou, China, analyzed with combined transcriptomic and microbiomic profiling to study in situ microbiome-immune interactions in CRC progression. machine-written summary
62 samples · 62 runs · CN · Age unknown · 2025 · 0.19 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 248 sample values (collection date, country, location locality, subject id) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolved
31 of 31 people sampled more than once (62 samples; median 2, up to 2 per person).
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 62 | 100% | 62 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 62 | 100% | 62 | |||
| collection_date | 62 | 100% | 62 | |||
| detailed_location | 62 | 100% | ||||
| location_locality | 62 | 100% | 62 |
Archive description
Colorectal cancer (CRC) is a multifactorial disease influenced by genetic, environmental, and microbial interactions. The role of the cancer microbiome in modulating immune responses and tumor progression remains inadequately explored. This study aims to elucidate the intricate relationships between the in situ microbiome and host immune response in CRC by integrating transcriptomic and microbiomic analyses. Understanding these interactions could provide insights into the mechanisms of CRC progression and identify potential therapeutic targets, particularly for improving immune therapy efficacy.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.68. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.title · “Colorectal Cancer”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN46220421 | collection_date | 2023 | R1 | 0.90 | biosample.attribute:collection_date | 2023 |
| SAMN46220421 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: suhzou |
| SAMN46220421 | location_locality | Suzhou | R1 | 0.75 | biosample.attribute:geo_loc_name | China: suhzou |
| SAMN46220421 | subject_id | 01 | R1 | 0.70 | sample.name_rule:library_name | P-01-CA-C1 |
Sequencing
62 runs over 62 samples · mean 0.21 Gbp per run (median 0.19 Gbp, total 13.07 Gbp; 62 runs with a base count) · layout SINGLE 62 · platform COMPLETE_GENOMICS 62 · models Complete Genomics (62) · 0% of runs with a Sandpiper profile · first public 2025-01-14
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA1209391.csv.gz (2.2 KB) · parquet (70.8 KB) — all 62 samples, every field with route and confidence · PRJNA1209391_determinations.csv.gz (2.5 KB) — 248 evidence rows