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PRJNA1209849 SRP558397

Gut metagenomics of centenarians in Jiangxi, China

Gut metagenomics Raw sequence reads

Cross-sectional study of 1 fecal metagenome sample from centenarians in Jiangxi, China, exploring gut microbiota characteristics, linked to isolation of a candidate anti-aging probiotic strain. machine-written summary

7 samples · 7 runs · CN · Elderly · 2025 · 8.25 Gbp / sample

Sources
○Sequence archive○Abstract / description✓Full text 21✓Supplementary tables 21–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
○ Sequence archiverecords read; no usable sample values
○ Abstract / descriptionread; no usable statement
✓ Full text21 sample values (collection date, country, location region) · PMC12419854
✓ Supplementary tables21 sample values (age, bmi, sex)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design observational_with_procedure

Samples at a glance
1 country
Age
elderly7
Sex
female7
Country
CN7
Body site
primary7
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 6 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.25 Gbp per sample0130Gbp
Community composition
Faecalibacterium 10.4%Prevotella 9.1%Roseburia 6.6%Fimenecus 5.5%Bacteroides 4.2%Ruminococcoides 4.1%Gemmiger 3.3%Phocaeicola 3.1%Alistipes 2.8%PeH17 2.7%Vescimonas 2.2%Bifidobacterium 1.9%not assigned to a genus 4.0%other genera 39.8%

Genera, mean relative abundance over 1 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category7 100%
country7 100%7
health_condition0 0%
subject_id0 0%
age_at_collection_days7 100%7
bmi7 100%7
collection_date7 100%7
detailed_location7 100%
location_region7 100%7
sex7 100%7
Papers (1)
  • L-Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU-08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway. 2025 PMID 40643197 PMC12419854 own_data
Details
Archive description

Metagenomics were used to explore the characteristics of microbiota in the feces of centenarians

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of elderly by sonnet_x2 with confidence 0.62. Assay shotgun_dna.

  • host study.description · “microbiota in the feces of centenarians”
  • body site study.description · “feces of centenarians”
  • life stage study.description · “feces of centenarians”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SRR32048609age_at_collection_days36890.2R20.75paper.supp.ACEL-24-e70166-s001.docx[table1!Age]Fb7 Age 101
SRR32048609bmi17.82R20.75paper.supp.ACEL-24-e70166-s001.docx[table1!Body Mass Index (BMI)]Fb7 BMI 17.82
SRR32048609collection_date2019R30.70paper.fulltext.methodsZhanggong District, Ganzhou City, Jiangxi Province, China, in 2019
SRR32048609countryCNR30.70paper.fulltext.methodsJiangxi Province, China
SRR32048609location_regionJiangxi ProvinceR30.70paper.fulltext.methodsFecal Samples From Centenarians in Jiangxi Province, China
SRR32048609sexfemaleR20.75paper.supp.ACEL-24-e70166-s001.docx[table1!Sex]Fb7 Female
Sequencing

7 runs over 7 samples · mean 8.23 Gbp per run (median 8.25 Gbp, total 57.61 Gbp; 7 runs with a base count) · layout PAIRED 7 · platform ILLUMINA 7 · models Illumina NovaSeq 6000 (7) · 100% of runs with a Sandpiper profile · first public 2025-01-21

Authors (9)

Xu T first · Wu X · Zhang Y · Cai Y · Zhang X · Zeng Q · Luo J · Wei J · Chen T last

Downloads

PRJNA1209849.csv.gz (1.1 KB) · parquet (69.6 KB) — all 7 samples, every field with route and confidence · PRJNA1209849_determinations.csv.gz (1.1 KB) — 42 evidence rows

Samples (7 · every field this project has values for · hover a cell for its source)
Loading the sample table…