Gut virome in heart failure patients vs controls, Beijing
Case-control study of 93 gut metagenome samples (67 adult, 26 elderly) from heart failure patients and non-HF controls in Beijing, China, examining gut virus association with heart failure. machine-written summary
93 samples · 93 runs · CN · Adult · 2025 · 6.90 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 558 sample values (age, country, health condition, health condition detail, location locality, sex) |
| ✓ Abstract / description | 93 sample values (subject id) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 92 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 93 | 100% | ||||
| country | 93 | 100% | 93 | |||
| health_condition | 93 | 100% | 93 | |||
| subject_id | 93 | 100% | 93 | |||
| age_at_collection_days | 93 | 100% | 93 | |||
| detailed_location | 93 | 100% | ||||
| health_condition_detail | 93 | 100% | 93 | |||
| location_locality | 93 | 100% | 93 | |||
| sex | 93 | 100% | 93 |
Archive description
To explore the association between HF and gut virus, we carried out a thorough examination of the gut microbiota of 48 HF patients and 45 non-HF controls using metagenomic sequencing.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and elderly by opus_adjudicated with confidence 0.75. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- host study.description · “48 HF patients and 45 non-HF controls”
- body site study.description · “the gut microbiota of 48 HF patients”
- life stage sample.attr.age · “65 (n=62/93)”
- life stage sample.attr.age · “70 (n=31/93)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN46258149 | age_at_collection_days | 28489.5 | R1 | 0.70 | sample.attr.age | 78 |
| SAMN46258149 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Beijing |
| SAMN46258149 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:index | control 1 |
| SAMN46258149 | health_condition_detail | non-HF control subject per project description | R1 | 0.70 | sample.name_rule:index | control 1 |
| SAMN46258149 | location_locality | Beijing | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Beijing |
| SAMN46258149 | sex | male | R1 | 0.90 | sample.attr.sex | male |
| SAMN46258149 | subject_id | SAMN46258149 | R4 | 0.60 | design.one_sample_per_subject:description | 48 HF patients and 45 non-HF controls |
Sequencing
93 runs over 93 samples · mean 7.43 Gbp per run (median 6.90 Gbp, total 690.94 Gbp; 93 runs with a base count) · layout PAIRED 93 · platform ILLUMINA 93 · models Illumina HiSeq 4000 (93) · 99% of runs with a Sandpiper profile · first public 2025-03-03
Authors (0)
No author record.
Downloads
PRJNA1210837.csv.gz (3.6 KB) · parquet (74.7 KB) — all 93 samples, every field with route and confidence · PRJNA1210837_determinations.csv.gz (5.6 KB) — 651 evidence rows