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PRJNA1221063 SRP573487

Gut microbiota in a Chinese healthy lifestyle cohort

Project of gut microbiota analysis based on the Healthy Lifestyle Promotion Cohort in China

Cross-sectional metagenomic study of 370 gut microbiome samples from general adults in China, part of the Healthy Lifestyle Promotion Cohort, aimed at understanding mechanisms underlying chronic and mental diseases. machine-written summary

370 samples · 370 runs · CN · Adult · 2025 · 7.10 Gbp / sample

Sources
✓Sequence archive 740–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive740 sample values (collection date, country)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult370
Country
CN370
Body site
primary370
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 369 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.10 Gbp per sample0130Gbp
Community composition
Blautia_A 11.4%Faecalibacterium 6.0%Bifidobacterium 5.5%Roseburia 5.1%Phocaeicola 4.2%Mediterraneibacter 4.2%Bacteroides 3.8%Prevotella 3.4%Escherichia 3.0%Ruminococcoides 2.9%Streptococcus 2.8%Collinsella 2.6%not assigned to a genus 3.5%other genera 41.7%

Genera, mean relative abundance over 367 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category370 100%
country370 100%370
health_condition0 0%
subject_id0 0%
collection_date370 100%370
Details
Archive description

The project conducts metagenomic sequencing of gut microbiota based on the data of Healthy Lifestyle Promotion Cohort, which recruited general adults in China. This project plans to jointly analyze these gut microbiome data and population metadata, with the main aim of understanding the potential mechanisms underlying multiple chronic and mental diseases, thereby providing a basis for disease prevention and control.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host study.description · “recruited general adults in China”
  • body site run.scientific_name · “human gut metagenome”
  • life stage study.description · “recruited general adults in China”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN46725436collection_date2023R10.90biosample.attribute:collection_date2023
SAMN46725436countryCNR10.90sample.attr.geo_loc_nameChina
Sequencing

370 runs over 370 samples · mean 7.21 Gbp per run (median 7.10 Gbp, total 2,668.07 Gbp; 370 runs with a base count) · layout PAIRED 370 · platform ILLUMINA 370 · models Illumina NovaSeq 6000 (370) · 99% of runs with a Sandpiper profile · first public 2025-10-02 – 2025-10-23

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1221063.csv.gz (8.0 KB) · parquet (81.9 KB) — all 370 samples, every field with route and confidence · PRJNA1221063_determinations.csv.gz (3.5 KB) — 740 evidence rows

Samples (370 · every field this project has values for · hover a cell for its source)
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