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PRJNA1225421 SRP573961

ECoMiD longitudinal gut microbiome cohort in Ecuador

Microbiome data from the ECoMiD cohort study in Ecuador

210 samples from the ECoMiD longitudinal cohort study in Ecuador. No health conditions, interventions, or demographic details are specified in the available sources. machine-written summary

210 samples · 210 runs · EC · Infant / toddler · 2025 · 2.76 Gbp / sample

Sources
✓Sequence archive 416○Abstract / description✓Full text 420✓Supplementary tables 1,336–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive416 sample values (country, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text420 sample values (collection date, health condition) · PMC12764814
✓ Supplementary tables1,336 sample values (age, family id, family role, sex, shared setting id, shared setting type, timepoint)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant100
unknown57
neonate53
Condition
healthy_control210
Sex
male82
female71
Country
EC210
Body site
primary210
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 2 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 131 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 73 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 4 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.76 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinalhouseholdsmother–infant

32 of 137 people sampled more than once (101 samples; median 4, up to 4 per person) · follow-up median 18 mo (max 18 mo) · median interval between samples 3 mo (time from age at collection). Schedule stated by the source: “Children sampled at 1 week, 3 months, 6 months, and 18 months; mothers sampled once at week 37 of pregnancy.” (time origin: birth).

EB1001EB1001 (child): day 0EB1001 (child): day 83EB1001 (child): day 173EB1001 (child): day 533EB1002EB1002 (child): day 0EB1002 (child): day 83EB1002 (child): day 173EB1002 (child): day 533EB1003EB1003 (child): day 0EB1003 (child): day 83EB1003 (child): day 173EB1003 (child): day 533EB1004EB1004 (child): day 0EB1004 (child): day 83EB1004 (child): day 173EB1004 (child): day 533EB1007EB1007 (child): day 0EB1007 (child): day 533EB1101EB1101 (child): day 0EB1101 (child): day 83EB1101 (child): day 173EB1101 (child): day 533EB1102EB1102 (child): day 0EB1102 (child): day 83EB1102 (child): day 173EB1102 (child): day 533EB1103EB1103 (child): day 0EB1103 (child): day 83EB1103 (child): day 173EB1103 (child): day 533EB1104EB1104 (child): day 0EB1104 (child): day 83EB1104 (child): day 173EB1104 (child): day 533EB1106EB1106 (child): day 0EB1106 (child): day 83EB1106 (child): day 173EB1106 (child): day 533EB1107EB1107 (child): day 0EB1107 (child): day 533BB2002BB2002 (child): day 0BB2002 (child): day 83BB2002 (child): day 173BB2002 (child): day 533BB2003BB2003 (child): day 0BB2003 (child): day 83BB2003 (child): day 173BB2003 (child): day 533BB2009BB2009 (child): day 0BB2009 (child): day 533BB2101BB2101 (child): day 0BB2101 (child): day 533BB2202BB2202 (child): day 0BB2202 (child): day 90BB2204BB2204 (child): day 0BB2204 (child): day 83BB2204 (child): day 173BB2204 (child): day 533BB2205BB2205 (child): day 0BB2205 (child): day 533BB2206BB2206 (child): day 0BB2206 (child): day 533BB2301BB2301 (child): day 0BB2301 (child): day 83BB2301 (child): day 173BB2301 (child): day 533BB2302BB2302 (child): day 0BB2302 (child): day 83BB2302 (child): day 173BB2302 (child): day 533BB2306BB2306 (child): day 0BB2306 (child): day 533MB3001MB3001 (child): day 0MB3001 (child): day 83MB3001 (child): day 173MB3001 (child): day 533MB3004MB3004 (child): day 0MB3004 (child): day 533MB3006MB3006 (child): day 0MB3006 (child): day 533MB3101MB3101 (child): day 0MB3101 (child): day 83MB3101 (child): day 173MB3101 (child): day 533MB3102MB3102 (child): day 0MB3102 (child): day 533MB3201MB3201 (child): day 0MB3201 (child): day 83MB3201 (child): day 173MB3201 (child): day 533TB6001TB6001 (child): day 0TB6001 (child): day 533TB6006TB6006 (child): day 0TB6006 (child): day 533ZB7001ZB7001 (child): day 0ZB7001 (child): day 83ZB7001 (child): day 173ZB7001 (child): day 533ZB7002ZB7002 (child): day 0ZB7002 (child): day 83ZB7002 (child): day 1730 d4 mo9 mo13 mo18 mo

Each row is one person (32 shown); dots are samples at days since that person's first sample; rows of one family are adjacent and coloured by role (mother, father, child, twin).

84 households: 53 mother–child pairs (mother at ~37 wk pregnancy, child 1 wk–18 mo) and 31 child-only households · 53 families with 106 sampled people (53 with a parent and a child) · 53 shared settings.

motherMchildC
53 × mother + child
family 1002EB1002 — child · 4 samplesCEB1002EM1002 — mother · 1 sampleMEM1002
family 1003EB1003 — child · 4 samplesCEB1003EM1003 — mother · 1 sampleMEM1003
family 1004EB1004 — child · 4 samplesCEB1004EM1004 — mother · 1 sampleMEM1004
family 1005EB1005 — child · 1 sampleCEB1005EM1005 — mother · 1 sampleMEM1005
family 1006EB1006 — child · 1 sampleCEB1006EM1006 — mother · 1 sampleMEM1006
family 1007EB1007 — child · 2 samplesCEB1007EM1007 — mother · 1 sampleMEM1007
family 1011EB1011 — child · 1 sampleCEB1011EM1011 — mother · 1 sampleMEM1011
family 1012EB1012 — child · 1 sampleCEB1012EM1012 — mother · 1 sampleMEM1012
family 1101EB1101 — child · 4 samplesCEB1101EM1101 — mother · 1 sampleMEM1101
family 1102EB1102 — child · 4 samplesCEB1102EM1102 — mother · 1 sampleMEM1102
family 1103EB1103 — child · 4 samplesCEB1103EM1103 — mother · 1 sampleMEM1103
family 1104EB1104 — child · 4 samplesCEB1104EM1104 — mother · 1 sampleMEM1104
family 1106EB1106 — child · 4 samplesCEB1106EM1106 — mother · 1 sampleMEM1106
family 1107EB1107 — child · 2 samplesCEB1107EM1107 — mother · 1 sampleMEM1107
family 2001BB2001 — child · 1 sampleCBB2001BM2001 — mother · 1 sampleMBM2001
family 2002BB2002 — child · 4 samplesCBB2002BM2002 — mother · 1 sampleMBM2002
family 2003BB2003 — child · 4 samplesCBB2003BM2003 — mother · 1 sampleMBM2003
family 2004BB2004 — child · 1 sampleCBB2004BM2004 — mother · 1 sampleMBM2004
family 2008BB2008 — child · 1 sampleCBB2008BM2008 — mother · 1 sampleMBM2008
family 2009BB2009 — child · 2 samplesCBB2009BM2009 — mother · 1 sampleMBM2009
family 2101BB2101 — child · 2 samplesCBB2101BM2101 — mother · 1 sampleMBM2101
family 2102BB2102 — child · 1 sampleCBB2102BM2102 — mother · 1 sampleMBM2102
family 2103BB2103 — child · 1 sampleCBB2103BM2103 — mother · 1 sampleMBM2103
family 2201BB2201 — child · 1 sampleCBB2201BM2201 — mother · 1 sampleMBM2201
household 1002 · 2 peoplehousehold 1002EB1002 — member · 4 samplesEB1002EM1002 — member · 1 sampleEM1002
household 2206 · 2 peoplehousehold 2206BB2206 — member · 2 samplesBB2206BM2206 — member · 1 sampleBM2206
household 2302 · 2 peoplehousehold 2302BB2302 — member · 4 samplesBB2302BM2302 — member · 1 sampleBM2302
household 2304 · 2 peoplehousehold 2304BB2304 — member · 1 sampleBB2304BM2304 — member · 1 sampleBM2304
household 2305 · 2 peoplehousehold 2305BB2305 — member · 1 sampleBB2305BM2305 — member · 1 sampleBM2305
household 2306 · 2 peoplehousehold 2306BB2306 — member · 2 samplesBB2306BM2306 — member · 1 sampleBM2306
household 2308 · 2 peoplehousehold 2308BB2308 — member · 1 sampleBB2308BM2308 — member · 1 sampleBM2308
household 2311 · 2 peoplehousehold 2311BB2311 — member · 1 sampleBB2311BM2311 — member · 1 sampleBM2311

motherchildmember · circles are people (pale = no sequenced sample), arrows run donor → recipient and parent → child, curved lines join twins, partners and siblings, squares are shared settings or families without recorded roles. Shown: 24 of 53 families (one per family structure, then more) · 8 of 53 shared settings. 137 people in the project overall.

Families (25 of 53)
familymemberssamples
1002mother + childSAMN47621679 · SAMN47621785 · SAMN47621786 · SAMN47621787 · SAMN47621815
1103mother + childSAMN47621685 · SAMN47621805 · SAMN47621806 · SAMN47621807 · SAMN47621825
2301mother + childSAMN47621670 · SAMN47621746 · SAMN47621747 · SAMN47621748 · SAMN47621771
2302mother + childSAMN47621671 · SAMN47621749 · SAMN47621750 · SAMN47621751 · SAMN47621772
3001mother + childSAMN47621696 · SAMN47621829 · SAMN47621830 · SAMN47621831 · SAMN47621843
2003mother + childSAMN47621660 · SAMN47621729 · SAMN47621730 · SAMN47621731 · SAMN47621759
2002mother + childSAMN47621659 · SAMN47621726 · SAMN47621727 · SAMN47621728 · SAMN47621758
3101mother + childSAMN47621704 · SAMN47621835 · SAMN47621836 · SAMN47621837 · SAMN47621847
2204mother + childSAMN47621665 · SAMN47621741 · SAMN47621742 · SAMN47621743 · SAMN47621768
1104mother + childSAMN47621686 · SAMN47621808 · SAMN47621809 · SAMN47621810 · SAMN47621826
1106mother + childSAMN47621687 · SAMN47621811 · SAMN47621812 · SAMN47621813 · SAMN47621827
1102mother + childSAMN47621684 · SAMN47621802 · SAMN47621803 · SAMN47621804 · SAMN47621824
1101mother + childSAMN47621683 · SAMN47621799 · SAMN47621800 · SAMN47621801 · SAMN47621823
3201mother + childSAMN47621711 · SAMN47621840 · SAMN47621841 · SAMN47621842 · SAMN47621850
7001mother + childSAMN47621716 · SAMN47621859 · SAMN47621860 · SAMN47621861 · SAMN47621866
1004mother + childSAMN47621681 · SAMN47621791 · SAMN47621792 · SAMN47621793 · SAMN47621817
1003mother + childSAMN47621680 · SAMN47621788 · SAMN47621789 · SAMN47621790 · SAMN47621816
7002mother + childSAMN47621862 · SAMN47621863 · SAMN47621864 · SAMN47621867
3102mother + childSAMN47621705 · SAMN47621838 · SAMN47621848
6001mother + childSAMN47621713 · SAMN47621851 · SAMN47621855
6006mother + childSAMN47621714 · SAMN47621854 · SAMN47621858
3006mother + childSAMN47621699 · SAMN47621834 · SAMN47621846
3004mother + childSAMN47621698 · SAMN47621832 · SAMN47621844
2306mother + childSAMN47621672 · SAMN47621754 · SAMN47621775
2206mother + childSAMN47621667 · SAMN47621745 · SAMN47621770

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 28.5%Prevotella 14.2%Bacteroides 4.5%Faecalibacterium 4.1%Streptococcus 3.7%Escherichia 3.6%Klebsiella 2.2%Roseburia 1.8%Succinivibrio 1.3%Phocaeicola 1.3%Mediterraneibacter 1.2%Blautia_A 1.1%not assigned to a genus 4.3%other genera 28.3%

Genera, mean relative abundance over 209 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category153 73%
country210 100%210
health_condition210 100%210
subject_id206 98%206
collection_date210 100%210
family_id206 98%206
family_role206 98%206
shared_setting_id206 98%206
shared_setting_type206 98%206
timepoint_label206 98%206
age_at_collection_days153 73%153
sex153 73%153
Papers (1)
  • Environmental exposures associated with the gut microbiome and resistome of pregnant women and children in Northwest Ecuador. 2025 PMID 41390665 PMC12764814 own_data
Details
Archive description

Microbiome sequencing data from the ECoMiD cohort study.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN47621659age_at_collection_days540.0R20.75paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[Analysis data!Age]2002 18m
SAMN47621659collection_date2019-05/2024-12R30.70paper.fulltext.methodsECoMiD study commenced enrollment in May 2019
SAMN47621659countryECR10.90biosample_attrEcuador
SAMN47621659family_id2002R20.85paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[No. of reads per metagenome!Household ID]2002 | 18m | BB200218mHN1e3_S11_R1_001.fastq.gz
SAMN47621659family_rolechildR20.60paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[No. of reads per metagenome!Age]2002 | 18m | BB200218mHN1e3_S11_R1_001.fastq.gz
SAMN47621659health_conditionhealthy_controlR30.70paper.fulltext.methodsinvestigate the gut microbiome’s interactions with enteric infections and environmental conditions
SAMN47621659sexfemaleR20.80paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[Analysis data!Children sex]2002 18m Female
SAMN47621659shared_setting_id2002R20.85paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[No. of reads per metagenome!Household ID]Household ID 2002 | BB200218mHN1e3_S11_R1_001.fastq.gz
SAMN47621659shared_setting_typehouseholdR20.85paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[No. of reads per metagenome!Household ID]Household ID 2002 | BB200218mHN1e3_S11_R1_001.fastq.gz
SAMN47621659subject_idBB2002R10.70sample.name_rule:library_nameBB200218m
SAMN47621659timepoint_labelmonth 18R20.80paper.supp.41467_2025_66567_MOESM3_ESM.xlsx[Analysis data!Age]2002 18m
Sequencing

210 runs over 210 samples · mean 3.55 Gbp per run (median 2.76 Gbp, total 745.00 Gbp; 210 runs with a base count) · layout PAIRED 210 · platform ILLUMINA 210 · models Illumina NovaSeq 6000 (150), NextSeq 2000 (60) · 100% of runs with a Sandpiper profile · first public 2025-11-23

Authors (0)

No author record.

Downloads

PRJNA1225421.csv.gz (8.4 KB) · parquet (81.7 KB) — all 210 samples, every field with route and confidence · PRJNA1225421_determinations.csv.gz (21.0 KB) — 2,172 evidence rows

Samples (210 · every field this project has values for · hover a cell for its source)
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