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PRJNA1227423 SRP565988

Gut microbiome in liver disease patients in Seoul, Korea

Metagenomic shotgun sequencing data of fecal samples from a liver disease cohort

Shotgun metagenomic sequencing of 176 fecal samples from liver disease patients in Seoul, Korea, to study gut microbiome changes associated with liver disease. machine-written summary

176 samples · 176 runs · KR · Age unknown · 2025 · 8.72 Gbp / sample

Sources
✓Sequence archive 704✓Abstract / description 176–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive704 sample values (country, location region, subject id, timepoint)
✓ Abstract / description176 sample values (health condition)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown176
Condition
liver_disease176
Country
KR176
Body site
primary176
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 90 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 86 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.72 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

54 of 86 people sampled more than once (144 samples; median 3, up to 3 per person). Schedule stated by the source: “Each subject sampled at up to three visits labeled V1, V2, V3; no calendar/day offsets stated”.

How longitudinal and relatedness information is derived

Community composition
Blautia_A 10.5%Bifidobacterium 8.9%Faecalibacterium 6.2%Collinsella 4.9%Prevotella 4.1%Phocaeicola 3.4%Roseburia 3.1%Mediterraneibacter 2.8%Anaerostipes 2.8%Fusicatenibacter 2.5%Megamonas 2.3%Bacteroides 2.3%not assigned to a genus 3.0%other genera 43.1%

Genera, mean relative abundance over 167 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country176 100%176
health_condition176 100%176
subject_id176 100%176
detailed_location176 100%
location_region176 100%176
timepoint_label176 100%176
Details
Archive description

These samples were sequenced to identify changes in gut microbiome from a liver disease patients in Korean individuals.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.85. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • host study.description · “liver disease patients in Korean individuals”
  • body site study.title · “fecal samples”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN46982776countryKRR10.90sample.attr.geo_loc_nameKorea: Seoul
SAMN46982776health_conditionliver_diseaseR40.50study.descriptionliver disease patients in Korean individuals
SAMN46982776location_regionSeoulR10.85biosample.attribute:geo_loc_nameKorea: Seoul
SAMN46982776subject_idKF001R10.70sample.name_rule:aliasalias: KF001-V1
SAMN46982776timepoint_labelV1R10.70sample.name_rule:aliasalias: KF001-V1
Sequencing

176 runs over 176 samples · mean 13.01 Gbp per run (median 8.72 Gbp, total 2,289.30 Gbp; 176 runs with a base count) · layout PAIRED 176 · platform ILLUMINA 176 · models Illumina NovaSeq 6000 (176) · 95% of runs with a Sandpiper profile · first public 2025-03-09

Authors (0)

No author record.

Downloads

PRJNA1227423.csv.gz (5.1 KB) · parquet (75.6 KB) — all 176 samples, every field with route and confidence · PRJNA1227423_determinations.csv.gz (8.0 KB) — 880 evidence rows

Samples (176 · every field this project has values for · hover a cell for its source)
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