Gut microbiota in functional constipation, Fuzhou, China
60 stool samples from functional constipation patients (with delayed or normal colonic transit time) and healthy controls in Fuzhou, China, analyzed via metagenomics and metabolomics in a case-control design. machine-written summary
60 samples · 60 runs · CN · Age unknown · 2025 · 10.48 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 340 sample values (collection date, country, health condition, health condition detail, latitude, location locality, longitude) |
| ✓ Abstract / description | 100 sample values (health condition detail, subject id) |
| ✓ Full text | 120 sample values (location region, location site) · PMC12134075 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 59 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 60 | 100% | 60 | |||
| health_condition | 20 | 33% | 20 | |||
| subject_id | 60 | 100% | 60 | |||
| collection_date | 60 | 100% | 60 | |||
| detailed_location | 60 | 100% | ||||
| health_condition_detail | 60 | 100% | 20 | 40 | ||
| latitude | 60 | 100% | 60 | |||
| location_locality | 60 | 100% | 60 | |||
| location_region | 60 | 100% | 60 | |||
| location_site | 60 | 100% | 60 | |||
| longitude | 60 | 100% | 60 |
- Correlation of the intestinal flora and its metabolites with the colonic transport function in functional constipation. 2025 PMID 40469730 PMC12134075 own_data
Archive description
Differences in the microbiota of functional constipation patients with different colonic transit functions assessed using macrogenomics
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host run.scientific_name · “human gut metagenome”
- body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN47233653 | collection_date | 2024-01 | R1 | 0.90 | biosample.attribute:collection_date | 2024-01 |
| SAMN47233653 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:FuZhou |
| SAMN47233693 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:sample_alias | H1 |
| SAMN47233693 | health_condition_detail | H | R1 | 0.70 | sample.name_rule:sample_alias | H1 |
| SAMN47233653 | health_condition_detail | mixed_case_control: Three groups: FC with delayed transit, FC with normal transit, healthy controls | R4 | 0.50 | paper.abstract | 20 FC patients with delayed colonic transit time, 20 FC patients with |
| SAMN47233653 | latitude | 26.1000 | R1 | 0.90 | biosample.attribute:lat_lon | 26.10 N 119.30 E |
| SAMN47233653 | location_locality | Fuzhou | R1 | 0.85 | biosample.attribute:geo_loc_name | China:FuZhou |
| SAMN47233653 | location_region | Fujian | R3 | 0.70 | paper.fulltext.methods | long-term residence in Fujian (more than 10 years) |
| SAMN47233653 | location_site | Second People's Hospital affiliated with Fujian University of Traditional Chinese Medicine | R3 | 0.70 | paper.fulltext.methods | Second People's Hospital affiliated with Fujian University of Traditional Chinese Medicine |
| SAMN47233653 | longitude | 119.3000 | R1 | 0.90 | biosample.attribute:lat_lon | 26.10 N 119.30 E |
| SAMN47233653 | subject_id | SAMN47233653 | R4 | 0.60 | design.one_sample_per_subject:abstract | Stool samples were collected from 60 participants |
Sequencing
60 runs over 60 samples · mean 10.72 Gbp per run (median 10.48 Gbp, total 642.94 Gbp; 60 runs with a base count) · layout PAIRED 60 · platform ILLUMINA 60 · models Illumina HiSeq 2500 (60) · 98% of runs with a Sandpiper profile · first public 2025-03-07
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA1232352.csv.gz (2.8 KB) · parquet (73.7 KB) — all 60 samples, every field with route and confidence · PRJNA1232352_determinations.csv.gz (4.5 KB) — 560 evidence rows