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PRJNA1241852 SRP573033

Dietary intervention gut microbiome in melanoma patients, Houston

dietary intervention trial in patients with melanoma

282 gut microbiome samples from melanoma patients in Houston, TX, collected as part of dietary intervention trials, including one in patients receiving immunotherapy for stage III-IV disease. machine-written summary

282 samples · 282 runs · US · Age unknown · 2026 · 7.00 Gbp / sample

Sources
✓Sequence archive 1,692✓Abstract / description 564–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,692 sample values (collection date, country, latitude, location locality, location region, longitude)
✓ Abstract / description564 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Controlled / prescribed diet or feeding regimen design randomized_controlled_trial · population other_cancer · Dietary intervention in melanoma patients, incl. immunotherapy recipients

“dietary intervention trial in patients with melanoma” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
unknown282
Condition
other_cancer282
Country
US282
Body site
primary282
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 1 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 9 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 221 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 50 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.00 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country282 100%282
health_condition282 100%282
subject_id0 0%
collection_date282 100%282
detailed_location282 100%
health_condition_detail282 100%282
latitude282 100%282
location_locality282 100%282
location_region282 100%282
longitude282 100%282
Details
Archive description

Microbiome data associated with the following studies: Dietary Intervention in Patients with a History of Melanoma (NCT03950635) and Effect of Diet on the Immune System in Patients With Stage III-IV Melanoma Receiving Immunotherapy, DIET Study (NCT04645680).

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site sample.attr.env_medium · “fecal material ENVO:00002003 (n=282/282)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN47572352collection_date2021-09/2023-08R10.90biosample.attribute:collection_date2021-09/2023-08
SAMN47572352countryUSR10.90sample.attr.geo_loc_nameUSA: Houston, TX
SAMN47572352health_conditionother_cancerR40.50study.descriptionDietary Intervention in Patients with a History of Melanoma
SAMN47572352health_condition_detailmelanoma patients receiving dietary intervention and/or immunotherapyR40.50study.descriptionDietary Intervention in Patients with a History of Melanoma
SAMN47572352latitude29.7100R10.90biosample.attribute:lat_lon29.71 N 95.40 W
SAMN47572352location_localityHoustonR10.85biosample.attribute:geo_loc_nameUSA: Houston, TX
SAMN47572352location_regionTexasR10.75biosample.attribute:geo_loc_nameUSA: Houston, TX
SAMN47572352longitude-95.4000R10.90biosample.attribute:lat_lon29.71 N 95.40 W
Sequencing

282 runs over 282 samples · mean 7.73 Gbp per run (median 7.00 Gbp, total 2,179.23 Gbp; 282 runs with a base count) · layout PAIRED 282 · platform ILLUMINA 282 · models Illumina NovaSeq 6000 (236), Illumina HiSeq X (46) · 0% of runs with a Sandpiper profile · first public 2026-04-19

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA1241852.csv.gz (7.5 KB) · parquet (80.5 KB) — all 282 samples, every field with route and confidence · PRJNA1241852_determinations.csv.gz (13.3 KB) — 2,256 evidence rows

Samples (282 · every field this project has values for · hover a cell for its source)
Loading the sample table…