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PRJNA1243897 SRP575335

Gut microbiome, fiber-enriched sourdough croissant intervention

Gut microbiome of people consuming a sourdough-leavened croissant enriched with fiber

62 samples from healthy adults in an intervention study comparing a sourdough-leavened croissant enriched with fiber (4.8 g/100 g) to a control croissant (1.3 g/100 g) consumed for 2 weeks. machine-written summary

62 samples · 62 runs · Adult · 2025 · 8.17 Gbp / sample

Sources
✓Sequence archive 495✓Abstract / description 124–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive495 sample values (age, bmi, collection date, intervention, intervention detail, sex, subject id, timepoint)
✓ Abstract / description124 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention · arms resolved

RPrebiotic / dietary fibre supplement: 16 people · 31 samplesprebiotic / fibre 16 people · 31 samplesPlacebo / sham arm (sample level only): 16 people · 31 samplesplacebo 16 people · 31 samples
randomised to parallel arms

Prebiotic / dietary fibre supplement design randomized_controlled_trial · population healthy_control · Fiber-enriched sourdough croissant (4.8 g/100g) vs control croissant for 2 weeks

“croissant enriched with dietary fibers) for 2 weeks” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
Age
adult62
Condition
healthy_control62
Sex
male34
female28
Body site
primary62
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 55 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 7 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.17 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

30 of 32 people sampled more than once (60 samples; median 2, up to 2 per person) · follow-up median 1 d (max 1 d) · median interval between samples 1 d (time from collection dates). Schedule stated by the source: “Fecal samples collected at baseline (T0) and after a 2-week breakfast intervention (T2) for each participant.” (time origin: intervention_start); stated follow-up 14 d.

M101M101: day 0M101: day 1M102M102: day 0M102: day 1M103M103: day 0M103: day 1M104M104: day 0M104: day 1M105M105: day 0M105: day 1M106M106: day 0M106: day 1M107M107: day 0M107: day 1M108M108: day 0M108: day 1M109M109: day 0M109: day 1M110M110: day 0M110: day 1M111M111: day 0M111: day 1M112M112: day 0M112: day 1M113M113: day 0M113: day 1M114M114: day 0M114: day 1M115M115: day 0M115: day 1M201M201: day 0M201: day 1M202M202: day 0M202: day 1M203M203: day 0M203: day 1M205M205: day 0M205: day 1M206M206: day 0M206: day 1M207M207: day 0M207: day 1M208M208: day 0M208: day 1M209M209: day 0M209: day 1M210M210: day 0M210: day 1M211M211: day 0M211: day 1M212M212: day 0M212: day 1M213M213: day 0M213: day 1M214M214: day 0M214: day 1M215M215: day 0M215: day 1M216M216: day 0M216: day 10 d0 d0 d1 d1 d

Each row is one person (30 shown); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition
Ruminococcoides 11.9%Faecalibacterium 6.6%Blautia_A 6.3%Bacteroides 5.9%Roseburia 5.5%Bifidobacterium 5.3%Phocaeicola 4.2%Gemmiger 3.5%Alistipes 3.0%Collinsella 2.7%Mediterraneibacter 2.7%Dialister 1.9%not assigned to a genus 4.3%other genera 36.3%

Genera, mean relative abundance over 59 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category62 100%
country0 0%
health_condition62 100%62
subject_id62 100%62
age_at_collection_days62 100%62
collection_date62 100%62
health_condition_detail62 100%62
intervention62 100%62
intervention_detail62 100%62
sex62 100%62
timepoint_label62 100%62
bmi61 98%61
Papers (1)
  • Consumption of a Sourdough-Leavened Croissant Enriched with a Blend of Fibers Influences Fasting Blood Glucose in a Randomized Controlled Trial in Healthy Subjects. 2024 PMID 39179206 own_data
Details
Archive description

Gut microbiome of people consuming a sourdough-leavened croissant enriched with fiber (4.8 g/100 g, croissant enriched with dietary fibers) for 2 weeks. The control group consumed a control croissant with 1.3 g/100 g.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome”
  • life stage sample.attr.age · “25 (n=62/62)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN47629765age_at_collection_days8766.0R10.85sample.attr.age24
SAMN47629765bmi21.5R10.90sample.attr.bmi21.5
SAMN47629765collection_date2025-01-01R10.90biosample.attribute:collection_date2025-01-01
SAMN47629765health_conditionhealthy_controlR40.50paper.abstractThirty-two healthy participants were randomly allocated to 2 groups
SAMN47629765health_condition_detailhealthy participantsR40.50paper.abstractThirty-two healthy participants were randomly allocated to 2 groups
SAMN47629765interventionprebiotic_or_fibreR10.80biosample.attribute:GroupGroup: FIBCRO
SAMN47629765intervention_detailfiber-enriched croissant (4.8 g/100g)R10.80biosample.attribute:GroupGroup: FIBCRO
SAMN47629765sexmaleR10.90sample.attr.gendermale
SAMN47629765subject_idM101R10.85sample.attr.subjectM101
SAMN47629765timepoint_labelbaselineR10.85sample.attr.timebaseline
Sequencing

62 runs over 62 samples · mean 8.55 Gbp per run (median 8.17 Gbp, total 529.81 Gbp; 62 runs with a base count) · layout PAIRED 62 · platform ILLUMINA 62 · models Illumina HiSeq 4000 (62) · 95% of runs with a Sandpiper profile · first public 2025-04-01

Authors (0)

No author record.

Downloads

PRJNA1243897.csv.gz (3.1 KB) · parquet (73.4 KB) — all 62 samples, every field with route and confidence · PRJNA1243897_determinations.csv.gz (5.4 KB) — 619 evidence rows

Samples (62 · every field this project has values for · hover a cell for its source)
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