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PRJNA1247984 SRP577246

Longitudinal gut metagenomes from Arkhangelsk, Russia residents

Shotgun Metagenomic Sequencing of Fecal Samples from Arkhangelsk, Northwestern Russia

350 fecal metagenomic samples from residents of Arkhangelsk, Northwestern Russia, collected longitudinally (two timepoints per participant, 2015-2017 and 2022), comparing microbiome annotation methods with BMI-related microbiota changes as a key variable. machine-written summary

350 samples · 350 runs · RU · Age unknown · 2025 · 6.88 Gbp / sample

Sources
✓Sequence archive 2,800○Abstract / description✓Full text 350○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive2,800 sample values (collection date, country, latitude, location locality, location region, longitude, sex, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text350 sample values (location site) · PMC12660995
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design observational_with_procedure

Samples at a glance
1 sampling locations · 1 country
Age
unknown350
Sex
female220
male130
Country
RU350
Body site
primary350
Collected 2015–2022
2015: 8 samples2016: 108 samples2017: 59 samples2022: 175 samples20152022
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 10 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 303 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 37 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.88 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

175 of 175 people sampled more than once (350 samples; median 2, up to 2 per person) · follow-up median 6.0 y (max 7.0 y) · median interval between samples 6.0 y (time from collection dates). Schedule stated by the source: “two samples per subject, one in 2015-2017 and another in 2022, ~five-year intervals” (time origin: baseline); stated follow-up 5.0 y.

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Each row is one person (36 shown of 175); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country350 100%350
health_condition0 0%
subject_id350 100%350
collection_date350 100%350
detailed_location350 100%
latitude350 100%350
location_locality350 100%350
location_region350 100%350
location_site350 100%350
longitude350 100%350
sex350 100%350
Papers (1)
  • Comparing alignment and de-novo approaches for gut microbiota metagenomic data analysis reveals differences in taxonomic resolution and novel functional insights. 2025 PMID 41309890 PMC12660995 own_data
Details
Archive description

Shotgun metagenomic sequencing of fecal samples collected from the residents of Arkhangelsk, Northwestern Russia</p><p>Paired samples were collected from 175 patients in 2016-2017 and 2022.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.68. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “Fecal Samples from Arkhangelsk”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN47836770collection_date2017-06-26R10.90biosample.attribute:collection_date2017-06-26
SAMN47836770countryRUR10.90sample.attr.geo_loc_nameRussia: Arkhangelsk
SAMN47836770latitude64.5425R10.90biosample.attribute:lat_lon64.542465 N 40.537319 E
SAMN47836770location_localityArkhangelskR10.85biosample.attribute:geo_loc_nameRussia: Arkhangelsk
SAMN47836770location_regionArkhangelskayaR10.60biosample.attribute:lat_lon64.542465 N 40.537319 E
SAMN47836770location_siteKnow Your Heart (KYH) studyR30.70paper.fulltext.methodscollected in 2015–2017 as part of the Know Your Heart
SAMN47836770longitude40.5373R10.90biosample.attribute:lat_lon64.542465 N 40.537319 E
SAMN47836770sexfemaleR10.90sample.attr.host_sexfemale
SAMN47836770subject_id1000954R10.85sample.attr.host_subject_id1000954
Sequencing

350 runs over 350 samples · mean 7.04 Gbp per run (median 6.88 Gbp, total 2,463.20 Gbp; 350 runs with a base count) · layout PAIRED 350 · platform DNBSEQ 350 · models DNBSEQ-G400 (350) · 0% of runs with a Sandpiper profile · first public 2025-04-09 – 2025-04-13

Authors (11)

Kuzmichenko P first · Fedorov D · Galeeva J · Postoeva A · Krieger E · Kudryavtsev A · Pavlenko A · Vvedensky A · Starikova E · Govorun V · Ilina E last

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata

Downloads

PRJNA1247984.csv.gz (12.3 KB) · parquet (86.7 KB) — all 350 samples, every field with route and confidence · PRJNA1247984_determinations.csv.gz (22.3 KB) — 3,150 evidence rows

Samples (350 · every field this project has values for · hover a cell for its source)
Loading the sample table…