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PRJNA1249971 SRP578252

Pediatric IBD gut microbiome in Cincinnati, Ohio

Microbiome in pediatric inflammatory bowel disease (Part 1)

148 gut microbiome samples from children with inflammatory bowel disease (unspecified type) in Cincinnati, Ohio, USA. machine-written summary

148 samples · 148 runs · US · Child · 2025 · 4.96 Gbp / sample

One study deposited as 2 BioProjects (284 catalog samples together): PRJNA1249606 · PRJNA1249971 · show together

Sources
✓Sequence archive 888✓Abstract / description 296–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive888 sample values (collection date, country, latitude, location locality, location region, longitude)
✓ Abstract / description296 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
child148
Condition
ibd_unspecified148
Country
US148
Body site
primary148
Collected 2016–2018
2016: 4 samples2017: 123 samples2018: 21 samples20162018
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 14 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 131 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 2 samplesall projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.96 Gbp per sample0130Gbp
Community composition
Bacteroides 18.1%Phocaeicola 11.7%Roseburia 5.2%Alistipes 4.8%Prevotella 4.4%Faecalibacterium 3.1%Parabacteroides 2.6%Blautia_A 2.1%Cetobacterium_A 2.0%Bifidobacterium 1.5%Escherichia 1.4%Akkermansia 1.3%not assigned to a genus 6.4%other genera 35.2%

Genera, mean relative abundance over 145 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category148 100%
country148 100%148
health_condition148 100%148
subject_id0 0%
collection_date148 100%148
detailed_location148 100%
health_condition_detail148 100%148
latitude148 100%148
location_locality148 100%148
location_region148 100%148
longitude148 100%148
Details
Archive description

Microbiome in Pediatric IBD

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of child by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_unknown_no_evidence”
  • body site external_curation.infant_catalog · “body_site_call stool”
  • life stage study.title · “Microbiome in pediatric inflammatory bowel disease”
  • life stage study.description · “Microbiome in Pediatric IBD”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN47926046collection_date2017-07-24R10.90biosample.attribute:collection_date2017-07-24
SAMN47926046countryUSR10.90sample.attr.geo_loc_nameUSA: Ohio, Cincinnati
SAMN47926046health_conditionibd_unspecifiedR40.50study.titlepediatric inflammatory bowel disease
SAMN47926046health_condition_detailInflammatory bowel disease in pediatric populationR40.50study.titlepediatric inflammatory bowel disease
SAMN47926046latitude39.1000R10.90biosample.attribute:lat_lon39.10 N 84.51 W
SAMN47926046location_localityCincinnatiR10.85biosample.attribute:geo_loc_nameUSA: Ohio, Cincinnati
SAMN47926046location_regionOhioR10.85biosample.attribute:geo_loc_nameUSA: Ohio, Cincinnati
SAMN47926046longitude-84.5100R10.90biosample.attribute:lat_lon39.10 N 84.51 W
Sequencing

148 runs over 148 samples · mean 5.76 Gbp per run (median 4.96 Gbp, total 853.03 Gbp; 148 runs with a base count) · layout PAIRED 148 · platform ILLUMINA 148 · models NextSeq 500 (148) · 98% of runs with a Sandpiper profile · first public 2025-04-14 – 2025-04-20

Authors (0)

No author record.

Downloads

PRJNA1249971.csv.gz (4.8 KB) · parquet (76.5 KB) — all 148 samples, every field with route and confidence · PRJNA1249971_determinations.csv.gz (7.4 KB) — 1,184 evidence rows

Samples (148 · every field this project has values for · hover a cell for its source)
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