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PRJNA1257550 SRP584319

Gut microbiota and eczema in Hong Kong birth cohorts

Role of gut microbiota in eczema development

1737 samples from two longitudinal birth cohorts in Hong Kong, studying the role of gut microbiota in eczema development. machine-written summary

1,737 samples · 1,737 runs · HK · Infant / toddler · 2025 · 5.45 Gbp / sample

Sources
✓Sequence archive 3,027○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive3,027 sample values (collection date, country)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown1,737
Country
HK1,737
Body site
primary1,737
Collected 2017–2023
2017: 23 samples2018: 240 samples2019: 36 samples2020: 215 samples2021: 567 samples2022: 169 samples2023: 40 samples20172023
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 136 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 89 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 16 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 20 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 174 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1,134 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 161 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 6 samplesall projects, 100–300 Gbp: 106 samples (0 %)this project, 100–300 Gbp: 1 samplesall projects, ≥ 300 Gbp: 9 samples (0 %)project median 5.45 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 37.7%Bacteroides 7.0%Escherichia 5.8%Phocaeicola 5.4%Streptococcus 3.2%Klebsiella 3.0%Enterococcus 2.6%Collinsella 2.3%Blautia_A 2.0%Mediterraneibacter 2.0%Faecalibacterium 1.8%Veillonella 1.2%not assigned to a genus 2.5%other genera 23.5%

Genera, mean relative abundance over 1,450 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country1,737 100%1,737
health_condition0 0%
subject_id0 0%
collection_date1,290 74%1,290
Details
Archive description

Two longitudinal birth cohorts were used to investigate the role of gut microbiota in eczema.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “Role of gut microbiota in eczema”
  • body site study.description · “the role of gut microbiota in eczema.”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN48324306collection_date2021-03-18R10.85biosample.attribute:collection_date2021-03-18T00:00:00Z
SAMN48324306countryHKR10.90biosample_attrHong Kong
Sequencing

1,737 runs over 1,737 samples · mean 5.63 Gbp per run (median 5.45 Gbp, total 9,774.59 Gbp; 1,737 runs with a base count) · layout PAIRED 1,737 · platform ILLUMINA 1,737 · models Illumina NovaSeq 6000 (1,737) · 83% of runs with a Sandpiper profile · first public 2025-05-28

Authors (0)

No author record.

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA1257550.csv.gz (47.0 KB) · parquet (144.8 KB) — all 1,737 samples, every field with route and confidence · PRJNA1257550_determinations.csv.gz (22.8 KB) — 3,027 evidence rows

Samples (1,737 · every field this project has values for · hover a cell for its source)
Loading the sample table…