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PRJNA1258282 SRP582874

Bismuth subsalicylate effect on adult gut microbiome (USA)

The effect of bismuth subsalicylate on the gut microbiome

Longitudinal study of 124 samples from adults in the USA examining the effect of bismuth subsalicylate on the gut microbiome. machine-written summary

124 samples · 124 runs · US · Adult · 2026 · 5.75 Gbp / sample

Sources
✓Sequence archive 868–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive868 sample values (age, bmi, collection date, country, latitude, location region, longitude)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

design single_arm_before_after

Samples at a glance
1 sampling locations · 1 country
Age
adult124
Country
US124
Body site
primary124
Collected 2023–2024
2023: 13 samples2024: 111 samples20232024
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 123 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 5.75 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category124 100%
country124 100%124
health_condition0 0%
subject_id0 0%
age_at_collection_days124 100%124
bmi124 100%124
collection_date124 100%124
detailed_location124 100%
latitude124 100%124
location_region124 100%124
longitude124 100%124
Papers (1)
  • Bismuth subsalicylate profoundly alters gut microbiome and immunity with increased susceptibility to infection 2025 own_data
Details
Archive description

This study investigated the longitudinal effect of bismuth subsalicylate on the gut microbiome.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “effect of bismuth subsalicylate on the gut microbiome”
  • life stage sample.attr.host_age · “28 (n=124/124)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN48312366age_at_collection_days9496.5R10.85sample.attr.host_age26
SAMN48312366bmi27.1R10.90sample.attr.host_body_mass_index27.1
SAMN48312366collection_date2023-09-28R10.90biosample.attribute:collection_date2023-09-28
SAMN48312366countryUSR10.90sample.attr.geo_loc_nameUSA
SAMN48312366latitude38.9900R10.90biosample.attribute:lat_lon38.99 N 77.09 W
SAMN48312366location_regionMarylandR10.60biosample.attribute:lat_lon38.99 N 77.09 W
SAMN48312366longitude-77.0900R10.90biosample.attribute:lat_lon38.99 N 77.09 W
Sequencing

124 runs over 124 samples · mean 5.80 Gbp per run (median 5.75 Gbp, total 718.85 Gbp; 124 runs with a base count) · layout PAIRED 124 · platform ILLUMINA 124 · models NextSeq 1000 (124) · 0% of runs with a Sandpiper profile · first public 2026-07-02

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1258282.csv.gz (4.1 KB) · parquet (75.6 KB) — all 124 samples, every field with route and confidence · PRJNA1258282_determinations.csv.gz (5.9 KB) — 868 evidence rows

Samples (124 · every field this project has values for · hover a cell for its source)
Loading the sample table…