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PRJNA1258733 SRP591694

Longitudinal gut microbiome in rural Mexican infants

Human Gut Metagenome

Shotgun metagenomics of 156 samples from a longitudinal cohort of ten rural infants in Morelos, Mexico, sampled monthly from birth to 18 months to study early-life gut microbial development. machine-written summary

156 samples · 156 runs · MX · Infant / toddler · 2026 · 0.81 Gbp / sample

Sources
✓Sequence archive 321✓Abstract / description 156✓Full text 623✓Supplementary tables 504–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive321 sample values (collection date, country, subject id, timepoint)
✓ Abstract / description156 sample values (lifestyle detail)
✓ Full text623 sample values (collection date, lifestyle, location locality, location region) · PMC13317942
✓ Supplementary tables504 sample values (age, delivery mode, sex, subject id)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant156
Sex
female76
male50
Country
MX156
Body site
primary156
Collected 2015–2016
2015: 155 samples2016: 1 samples20152016
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 8 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 2 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 3 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 98 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 45 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.81 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

15 of 16 people sampled more than once (144 samples; median 11, up to 17 per person) · follow-up median 17 mo (max 17 mo) · median interval between samples 31 d (time from age at collection). Schedule stated by the source: “sampled monthly from birth to 18 months” (time origin: birth).

P02P02: day 0P02: day 31P02: day 61P02: day 92P02: day 122P02: day 153P02: day 183P02: day 214P02: day 244P02: day 274P02: day 305P02: day 335P02: day 366P02: day 396P02: day 427P02: day 518P04P04: day 0P04: day 31P04: day 61P04: day 92P04: day 122P04: day 153P04: day 183P04: day 214P04: day 244P04: day 274P04: day 305P04: day 335P04: day 366P04: day 396P04: day 457P04: day 487P04: day 518P05P05: day 0P05: day 31P05: day 61P05: day 92P05: day 122P05: day 153P05: day 183P05: day 214P05: day 244P05: day 274P05: day 305P05: day 335P05: day 457P05: day 487P06P06: day 0P06: day 30P06: day 61P06: day 91P06: day 122P06: day 152P06: day 183P06: day 213P06: day 243P06: day 365P06: day 456P07P07: day 0P07: day 61P07: day 122P07: day 183P07: day 244P07: day 274P07: day 305P07: day 366P07: day 427P07: day 518P09P09: day 0P09: day 30P09: day 61P09: day 91P09: day 122P09: day 152P09: day 183P09: day 213P09: day 243P09: day 304P09: day 365P09: day 426P10P10: day 0P10: day 61P10: day 92P10: day 153P10: day 183P10: day 213P11P11: day 0P11: day 31P11: day 61P11: day 122P11: day 153P11: day 183P11: day 274P11: day 305P11: day 335P11: day 366P11: day 396P11: day 518P15P15: day 0P15: day 31P15: day 61P15: day 92P15: day 122P15: day 153P15: day 214P15: day 244P15: day 274P15: day 305P15: day 366P15: day 396P15: day 427P15: day 457P15: day 487P15: day 518P19P19: day 0P19: day 61P19: day 92P19: day 153P19: day 214P19: day 244P19: day 274P19: day 305P19: day 335P19: day 366P19: day 396P19: day 4270 d4 mo9 mo13 mo17 mo

Each row is one person (10 shown of 15); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category156 100%
country156 100%156
health_condition0 0%
subject_id145 93%19126
collection_date156 100%1155
detailed_location156 100%
lifestyle156 100%156
lifestyle_detail156 100%156
location_locality156 100%156
location_region156 100%156
timepoint_label145 93%145
age_at_collection_days126 81%126
delivery_mode126 81%126
sex126 81%126
Papers (1)
  • Impact of maternal, infant, and household factors on early-life gut microbiome development in a rural setting. PMID 42127418 PMC13317942 curated
Details
Archive description

Shotgun metagenomics data from a unique longitudinal study of ten rural infants in Morelos, Mexico, sampled monthly from birth to 18 months, profiling bacterial gut microbiomes to explore early-life microbial development in a rural environment.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “Human Gut Metagenome”
  • body site study.description · “months, profiling bacterial gut microbiomes to explore”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.description · “of ten rural infants in Morelos, Mexico,”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SRR33958015age_at_collection_days122R20.75paper.supp.tableInfant age (month)=4
SRR33958170collection_date2016R10.85biosample.attribute:collection_datecollection_date: 2016
SRR33958015collection_date2015-03/2016-05R30.70paper.fulltext.methodsborn between March 2015 and May 2016
SRR33958015countryMXR10.90sample.attr.geo_loc_nameMexico
SRR33958015delivery_modevaginalR20.75paper.supp.tableMode of birth=Vaginal
SRR33958015lifestylerural_non_industrializedR30.70paper.fulltext.methodspredominantly rural character
SRR33958015lifestyle_detailrural community in Morelos, MexicoR40.50paper.abstractrural community in Morelos, Mexico
SRR33958015location_localityXoxocotlaR30.70paper.fulltext.methodsrural district in Xoxocotla
SRR33958015location_regionMorelosR30.70paper.fulltext.methodsin the state of Morelos, central Mexico
SRR33958015sexfemaleR20.75paper.supp.tableSex=Female
SRR33958019subject_id07R10.70sample.name_rule:library_namesXC07-16-02
SRR33958015subject_idP09R20.75paper.supp.tableInfant ID=P09
SRR33958015timepoint_label04R10.70sample.name_rule:library_namesXC09-04
Sequencing

156 runs over 156 samples · mean 0.82 Gbp per run (median 0.81 Gbp, total 128.28 Gbp; 156 runs with a base count) · layout PAIRED 156 · platform ILLUMINA 156 · models NextSeq 500 (156) · 0% of runs with a Sandpiper profile · first public 2026-06-21

Authors (8)

Parizadeh M first · Laforest-Lapointe I · Serrano-Vázquez A · Morán-Silva P · Rojas-Velázquez L · Torres J · Ximénez-García C · Arrieta MC last

Downloads

PRJNA1258733.csv.gz (5.0 KB) · parquet (75.7 KB) — all 156 samples, every field with route and confidence · PRJNA1258733_determinations.csv.gz (11.5 KB) — 1,604 evidence rows

Samples (156 · every field this project has values for · hover a cell for its source)
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