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PRJNA1263159 SRP585472

FMT for CDI cohort in Hong Kong, China

Fecal Microbiota Transplantation for CDI cohort

42 fecal metagenome samples from CDI recipients (pre- and post-FMT) and donors in Hong Kong, China, studying fecal microbiota transplantation as an intervention. machine-written summary

42 samples · 42 runs · HK · Age unknown · 2025 · 4.56 Gbp / sample

Sources
✓Sequence archive 401–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive401 sample values (country, health condition, health condition detail, intervention, latitude, location locality, location region, longitude)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention · arms resolved

before · no interventionbefore · no interventi25 samplesFMTFMT17 samples
single arm: samples before and on the intervention

14 people have samples in more than one arm.

Faecal microbiota transplantation design single_arm_before_after · population gi_infection_or_diarrhoea · FMT in CDI recipients, pre- and post-FMT, with donor samples

“CDI recipients (pre-FMT and post-FMT) and donors” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
unknown42
Condition
gi_infection_or_diarrhoea36
Country
HK42
Body site
primary42
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 4 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 37 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.56 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolvedFMT donor → recipient

14 of 21 people sampled more than once (34 samples; median 2, up to 5 per person). Schedule stated by the source: “pre-FMT and post-FMT timepoints per recipient” (time origin: FMT procedure).

Evidence of fmt donor recipient structure.

donor: SAMN48513381, SAMN48513382, SAMN48513383, SAMN48513385, SAMN48513386, SAMN48513387, SAMN48513388, SAMN48513389, SAMN48513390, SAMN48513391, SAMN48513393, SAMN48513400, SAMN48513401, SAMN48513403, SAMN48513404, SAMN48513405, SAMN48513406, SAMN48513407, SAMN48513408, SAMN48513410, SAMN48513414SAMN48513414 donor of SAMN48513381SAMN48513414 donor of SAMN48513382SAMN48513414 donor of SAMN48513382SAMN48513414 donor of SAMN48513400SAMN48513414 donor of SAMN48513383SAMN48513414 donor of SAMN48513401SAMN48513414 donor of SAMN48513385SAMN48513414 donor of SAMN48513386SAMN48513414 donor of SAMN48513386SAMN48513414 donor of SAMN48513403SAMN48513414 donor of SAMN48513387SAMN48513414 donor of SAMN48513404SAMN48513414 donor of SAMN48513388SAMN48513414 donor of SAMN48513405SAMN48513414 donor of SAMN48513389SAMN48513414 donor of SAMN48513406SAMN48513414 donor of SAMN48513390SAMN48513414 donor of SAMN48513407SAMN48513414 donor of SAMN48513391SAMN48513414 donor of SAMN48513408SAMN48513414 donor of SAMN48513393SAMN48513414 donor of SAMN48513410SAMN48513381 — recipient · 1 sampleR381SAMN48513382 — recipient · 1 sampleR382SAMN48513383 — recipient · 1 sampleR383SAMN48513385 — recipient · 1 sampleR385SAMN48513386 — recipient · 1 sampleR386SAMN48513387 — recipient · 1 sampleR387SAMN48513388 — recipient · 1 sampleR388SAMN48513389 — recipient · 1 sampleR389SAMN48513390 — recipient · 1 sampleR390SAMN48513391 — recipient · 1 sampleR391SAMN48513393 — recipient · 1 sampleR393SAMN48513400 — recipient · 1 sampleR400SAMN48513401 — recipient · 1 sampleR401SAMN48513403 — recipient · 1 sampleR403SAMN48513404 — recipient · 1 sampleR404SAMN48513405 — recipient · 1 sampleR405SAMN48513406 — recipient · 1 sampleR406SAMN48513407 — recipient · 1 sampleR407SAMN48513408 — recipient · 1 sampleR408SAMN48513410 — recipient · 1 sampleR410SAMN48513414 — donor · 1 sampleD414SAMN48513…
donor: SAMN48513376, SAMN48513377, SAMN48513378, SAMN48513395, SAMN48513396, SAMN48513397, SAMN48513412SAMN48513412 donor of SAMN48513376SAMN48513412 donor of SAMN48513395SAMN48513412 donor of SAMN48513377SAMN48513412 donor of SAMN48513396SAMN48513412 donor of SAMN48513378SAMN48513412 donor of SAMN48513397SAMN48513376 — recipient · 1 sampleR376SAMN48513377 — recipient · 1 sampleR377SAMN48513378 — recipient · 1 sampleR378SAMN48513395 — recipient · 1 sampleR395SAMN48513396 — recipient · 1 sampleR396SAMN48513397 — recipient · 1 sampleR397SAMN48513412 — donor · 1 sampleD412SAMN48513…
donor: SAMN48513379, SAMN48513380, SAMN48513398, SAMN48513399, SAMN48513413SAMN48513413 donor of SAMN48513379SAMN48513413 donor of SAMN48513398SAMN48513413 donor of SAMN48513380SAMN48513413 donor of SAMN48513399SAMN48513379 — recipient · 1 sampleR379SAMN48513380 — recipient · 1 sampleR380SAMN48513398 — recipient · 1 sampleR398SAMN48513399 — recipient · 1 sampleR399SAMN48513413 — donor · 1 sampleD413SAMN48513…
donor: SAMN48513375, SAMN48513394, SAMN48513411SAMN48513411 donor of SAMN48513375SAMN48513411 donor of SAMN48513394SAMN48513375 — recipient · 1 sampleR375SAMN48513394 — recipient · 1 sampleR394SAMN48513411 — donor · 1 sampleD411SAMN48513…
donor: SAMN48513384, SAMN48513402, SAMN48513415SAMN48513415 donor of SAMN48513384SAMN48513415 donor of SAMN48513402SAMN48513384 — recipient · 1 sampleR384SAMN48513402 — recipient · 1 sampleR402SAMN48513415 — donor · 1 sampleD415SAMN48513…
donor: SAMN48513392, SAMN48513409, SAMN48513416SAMN48513416 donor of SAMN48513392SAMN48513416 donor of SAMN48513409SAMN48513392 — recipient · 1 sampleR392SAMN48513409 — recipient · 1 sampleR409SAMN48513416 — donor · 1 sampleD416SAMN48513…

donorrecipient · circles are people (pale = no sequenced sample), arrows run donor → recipient and parent → child, curved lines join twins, partners and siblings, squares are shared settings or families without recorded roles. Shown: 6 linked groups from explicit relations. 21 people in the project overall.

How longitudinal and relatedness information is derived

Community composition
Escherichia 10.1%Blautia_A 8.1%Klebsiella 6.0%Bifidobacterium 5.5%Bacteroides 5.3%Mediterraneibacter 5.0%Phocaeicola 4.8%Enterococcus 3.5%Collinsella 2.5%Streptococcus 2.5%Faecalibacterium 2.4%Roseburia 2.1%not assigned to a genus 4.4%other genera 37.8%

Genera, mean relative abundance over 42 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country42 100%42
health_condition36 86%36
subject_id41 98%41
detailed_location42 100%
intervention42 100%42
latitude42 100%42
location_locality42 100%42
location_region42 100%42
longitude42 100%42
health_condition_detail36 86%36
timepoint_label36 86%36
Details
Archive description

This cohort contains the metagenomic sequencing data for CDI recipients (pre-FMT and post-FMT) and donors

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.scientific_name · “human metagenome”
  • body site study.title · “Fecal Microbiota Transplantation for CDI cohort”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN48513375countryHKR10.90sample.attr.geo_loc_nameChina: Hong Kong
SAMN48513375health_conditiongi_infection_or_diarrhoeaR10.85biosample.attribute:titletitle: pre-FMT
SAMN48513375health_condition_detailpre-FMTR10.85biosample.attribute:titletitle: pre-FMT
SAMN48513375interventionno_interventionR10.85biosample.attribute:titletitle: pre-FMT
SAMN48513375latitude22.3027R10.90biosample.attribute:lat_lon22.302711 N 114.177216 E
SAMN48513375location_localityHong KongR10.85biosample.attribute:geo_loc_nameChina: Hong Kong
SAMN48513375location_regionKowloon CityR10.60biosample.attribute:lat_lon22.302711 N 114.177216 E
SAMN48513375longitude114.1772R10.90biosample.attribute:lat_lon22.302711 N 114.177216 E
SAMN48513375subject_idFR0003R10.70sample.name_rule:aliasFR0003_1
SAMN48513375timepoint_labelpre-FMTR10.85biosample.attribute:titletitle: pre-FMT
Sequencing

42 runs over 42 samples · mean 5.15 Gbp per run (median 4.56 Gbp, total 216.10 Gbp; 42 runs with a base count) · layout PAIRED 42 · platform ILLUMINA 42 · models Illumina NovaSeq 6000 (42) · 100% of runs with a Sandpiper profile · first public 2025-05-18

Authors (0)

No author record.

Downloads

PRJNA1263159.csv.gz (2.1 KB) · parquet (71.8 KB) — all 42 samples, every field with route and confidence · PRJNA1263159_determinations.csv.gz (4.0 KB) — 401 evidence rows

Samples (42 · every field this project has values for · hover a cell for its source)
Loading the sample table…