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PRJNA1273656 SRP590711

Seaweed meal intervention and gut microbiome in Zhoushan, China

Arsenic Metabolism and Gut Microbiome Responses Following a Single Meal of Seaweeds in Humans

61 gut metagenome samples from Zhoushan, China, from a diet intervention study examining arsenic metabolism and gut microbiome/CAZyme responses to a single seaweed meal. machine-written summary

61 samples · 61 runs · CN · Age unknown · 2025 · 17.47 Gbp / sample

Sources
✓Sequence archive 299○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive299 sample values (collection date, country, location locality, subject id, timepoint)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Controlled / prescribed diet or feeding regimen design single_arm_before_after · population healthy_control · Single test meal containing seaweed, pre/post sampling

“a Single Meal of Seaweeds in Humans” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 country
Age
unknown61
Country
CN61
Body site
primary61
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 61 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 17.47 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

19 of 36 people sampled more than once (44 samples; median 2, up to 3 per person).

How longitudinal and relatedness information is derived

Community composition
Blautia_A 9.7%Escherichia 7.5%Bifidobacterium 7.0%Faecalibacterium 5.8%Roseburia 4.5%Bacteroides 3.8%Streptococcus 3.8%Anaerobutyricum 3.4%Gemmiger 3.1%Prevotella 2.7%Mediterraneibacter 2.4%Phocaeicola 2.4%not assigned to a genus 3.1%other genera 40.8%

Genera, mean relative abundance over 57 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country61 100%61
health_condition0 0%
subject_id61 100%61
collection_date61 100%61
detailed_location61 100%
location_locality61 100%61
timepoint_label55 90%55
Details
Archive description

This study utilized shotgun metagenomic sequencing to comprehensively investigate the effects of seaweed consumption on the human gut microbiome and its CAZyme repertoire.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.70. Assay shotgun_dna.

  • host study.title · “Following a Single Meal of Seaweeds in Humans”
  • host run.host_tax_id · “9606”
  • body site study.description · “the human gut microbiome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN48952664collection_date2023-07R10.90biosample.attribute:collection_date2023-07
SAMN48952664countryCNR10.90sample.attr.geo_loc_nameChina:ZhouShan
SAMN48952664location_localityZhoushanR10.85biosample.attribute:geo_loc_nameChina:ZhouShan
SAMN48952664subject_id1R10.70sample.name_rule:titletitle: F1-1
SAMN48952664timepoint_label1R10.70sample.name_rule:titletitle: F1-1
Sequencing

61 runs over 61 samples · mean 17.51 Gbp per run (median 17.47 Gbp, total 1,068.10 Gbp; 61 runs with a base count) · layout PAIRED 61 · platform ILLUMINA 61 · models Illumina MiSeq (61) · 93% of runs with a Sandpiper profile · first public 2025-09-21

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata

Downloads

PRJNA1273656.csv.gz (2.3 KB) · parquet (71.1 KB) — all 61 samples, every field with route and confidence · PRJNA1273656_determinations.csv.gz (3.4 KB) — 299 evidence rows

Samples (61 · every field this project has values for · hover a cell for its source)
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