Gut resistome in infants and adults with obesity, Kazakhstan
Case-control study of 247 gut metagenome samples from infants and adults in Kazakhstan, examining antibiotic resistance genes in relation to obesity. machine-written summary
247 samples · 247 runs · KZ · Infant / toddler · 2025 · 7.56 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 934 sample values (age, country, health condition, health condition detail, subject id) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal
32 of 64 people sampled more than once (78 samples; median 2, up to 4 per person) · follow-up median 12 mo (max 18 mo) · median interval between samples 11 mo (time from age at collection).
Each row is one person (31 shown of 32); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 240 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 247 | 100% | ||||
| country | 247 | 100% | 247 | |||
| health_condition | 165 | 67% | 165 | |||
| subject_id | 110 | 45% | 110 | |||
| age_at_collection_days | 247 | 100% | 247 | |||
| health_condition_detail | 165 | 67% | 165 |
Archive description
Antibiotic resistance genes in infants with and without obesity
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage verdict include”
- body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
- life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
- life stage study.title · “resistance genes in infants with and without”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN49793780 | age_at_collection_days | 548 | R1 | 0.75 | sample.attr.host_age | 1.5 |
| SAMN49793780 | country | KZ | R1 | 0.90 | biosample_attr | Kazakhstan |
| SAMN49793808 | health_condition | obesity | R1 | 0.70 | sample.name_rule:library_names | OB001M1_2 |
| SAMN49793808 | health_condition_detail | OB: Project description states the study is 'Antibiotic resistance genes in infants with and without obesity.' The 'OB' pref | R1 | 0.70 | sample.name_rule:library_names | OB001M1_2 |
| SAMN49793780 | subject_id | BM0010P1 | R1 | 0.70 | sample.name_rule:library_names | BM0010P1_18 |
Sequencing
247 runs over 247 samples · mean 7.57 Gbp per run (median 7.56 Gbp, total 1,869.42 Gbp; 247 runs with a base count) · layout PAIRED 227, SINGLE 20 · platform ILLUMINA 247 · models Illumina NovaSeq 6000 (247) · 97% of runs with a Sandpiper profile · first public 2025-07-28 – 2025-08-26
Authors (0)
No author record.
Downloads
PRJNA1286160.csv.gz (8.0 KB) · parquet (81.3 KB) — all 247 samples, every field with route and confidence · PRJNA1286160_determinations.csv.gz (9.0 KB) — 934 evidence rows