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PRJNA1290379 SRP600208

Infant gut microbiome by atopic risk, New York cohort

Infant stool

Longitudinal cohort study of 261 infant stool samples from New York, USA, comparing high atopic risk versus low atopic risk infants. machine-written summary

261 samples · 261 runs · US · Infant / toddler · 2026 · 7.35 Gbp / sample

Sources
✓Sequence archive 261○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive261 sample values (country)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC12851394
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
infant261
Country
US261
Body site
primary261
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 6 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 220 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 35 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.35 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 65.9%Streptococcus 5.3%Escherichia 3.4%Blautia_A 2.7%Collinsella 2.6%Mediterraneibacter 1.7%Klebsiella 1.6%Bacteroides 1.5%Pauljensenia 0.8%Faecalibacterium 0.8%Akkermansia 0.6%Thomasclavelia 0.6%not assigned to a genus 3.9%other genera 8.6%

Genera, mean relative abundance over 221 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category261 100%
country261 100%261
health_condition0 0%
subject_id0 0%
Papers (1)
Details
Archive description

Infant stools from high atopic risk versus low atopic risk infants

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “Infant stool”
  • body site study.description · “Infant stools from high atopic”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.title · “Infant stool”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN49918264countryUSR10.90biosample_attrUSA: New York
Sequencing

261 runs over 261 samples · mean 7.78 Gbp per run (median 7.35 Gbp, total 2,029.79 Gbp; 261 runs with a base count) · layout PAIRED 261 · platform ILLUMINA 261 · models NextSeq 500 (261) · 85% of runs with a Sandpiper profile · first public 2026-02-22

Authors (8)

Perdue TJ first · Newkirk CE · Beblavy R · Seppo AE · Davis EC · Sohn MB · Järvinen KM · Monaco CL last

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1290379.csv.gz (7.3 KB) · parquet (79.7 KB) — all 261 samples, every field with route and confidence · PRJNA1290379_determinations.csv.gz (1.1 KB) — 261 evidence rows

Samples (261 · every field this project has values for · hover a cell for its source)
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