Gut microbiome in Parkinson's disease, Melbourne, Australia
73 gut microbiome samples from adults and elderly participants in Melbourne, Australia, comparing healthy controls (55) with individuals with neurological/psychiatric conditions (18); study design "other." machine-written summary
73 samples · 73 runs · AU · Age unknown · 2025 · 3.22 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 501 sample values (age, collection date, country, health condition, health condition detail, location locality, sex) |
| ✓ Abstract / description | 73 sample values (subject id) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 72 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 73 | 100% | ||||
| country | 73 | 100% | 73 | |||
| health_condition | 73 | 100% | 73 | |||
| subject_id | 73 | 100% | 73 | |||
| age_at_collection_days | 73 | 100% | 73 | |||
| detailed_location | 73 | 100% | ||||
| health_condition_detail | 73 | 100% | 73 | |||
| location_locality | 73 | 100% | 73 | |||
| sex | 73 | 100% | 73 | |||
| collection_date | 63 | 86% | 63 |
- Differences in the gut microbiome across typical ageing and in Parkinson's disease. 2023 PMID 37150399 own_data
Archive description
Please refer to the studies osf.io registration page for further details. https://osf.io/52dg9
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and elderly by opus_adjudicated with confidence 0.70. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.title · “Gut Bacteria”
- life stage sample.attr.age · “63 (n=41/73)”
- life stage sample.attr.age · “69 (n=32/73)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN50304109 | age_at_collection_days | 12053.2 | R1 | 0.70 | sample.attr.age | 33 |
| SAMN50304109 | collection_date | 2019-07-03 | R1 | 0.90 | biosample.attribute:collection_date | 2019-07-03 |
| SAMN50304109 | country | AU | R1 | 0.90 | sample.attr.geo_loc_name | Australia: Melbourne |
| SAMN50304109 | health_condition | healthy_control | R1 | 0.90 | biosample_attr | Healthy Young |
| SAMN50304109 | health_condition_detail | Healthy Young | R1 | 0.90 | sample.attr.health_state | Healthy Young |
| SAMN50304109 | location_locality | Melbourne | R1 | 0.85 | biosample.attribute:geo_loc_name | Australia: Melbourne |
| SAMN50304109 | sex | female | R1 | 0.90 | sample.attr.sex | female |
| SAMN50304109 | subject_id | SAMN50304109 | R4 | 0.60 | design.one_sample_per_subject:abstract | healthy young (n = 22, 18-35 years), healthy older (n = 33, 50-80 years), and PD groups (n = 18, 50-80 years) |
Sequencing
73 runs over 73 samples · mean 3.34 Gbp per run (median 3.22 Gbp, total 244.15 Gbp; 73 runs with a base count) · layout PAIRED 73 · platform ILLUMINA 73 · models Illumina NovaSeq 6000 (73) · 99% of runs with a Sandpiper profile · first public 2025-08-01
Authors (0)
No author record.
Downloads
PRJNA1299468.csv.gz (3.4 KB) · parquet (74.4 KB) — all 73 samples, every field with route and confidence · PRJNA1299468_determinations.csv.gz (4.8 KB) — 574 evidence rows