Gut microbiota in Indian preterm infants with NEC
Whole-genome shotgun metagenomics of 22 samples from preterm neonates in India, studying necrotizing enterocolitis using a case-control design. machine-written summary
22 samples · 22 runs · IN · Infant / toddler · 2025 · 2.20 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 44 sample values (collection date, country) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 44 sample values (age, location region) · PMC12460237 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
design observational_with_procedure
Genera, mean relative abundance over 21 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 22 | 100% | ||||
| country | 22 | 100% | 22 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 22 | 100% | 22 | |||
| collection_date | 22 | 100% | 22 | |||
| detailed_location | 22 | 100% | ||||
| location_region | 22 | 100% | 22 |
- Characterization of gut microbiota signatures in Indian preterm infants with necrotizing enterocolitis: a shotgun metagenomic approach. PMID 41017911 PMC12460237 curated
Archive description
This study use whole genome (shotgun) metagenomics sequencing approach for identification of gut microbiota in Indian Preterm Infants with Necrotizing Enterocolitis
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler and neonate by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage verdict include”
- body site study.title · “Gut Microbiota Signatures in”
- body site study.description · “for identification of gut microbiota in Indian”
- life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
- life stage study.title · “in Indian Preterm Infants with Necrotizing Enterocolitis”
- life stage study.title · “Signatures in Indian Preterm Infants with Necrotizing”
- life stage study.description · “microbiota in Indian Preterm Infants with Necrotizing”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN50554612 | age_at_collection_days | 6 | R3 | 0.40 | paper.fulltext.results | Day of life on which stool sample was collected 6 |
| SAMN50554612 | collection_date | 2022-08-15 | R1 | 0.85 | biosample.attribute:collection_date | collection_date: 2022-08-15 |
| SAMN50554612 | country | IN | R1 | 0.90 | biosample_attr | India |
| SAMN50554612 | location_region | Chandigarh | R3 | 0.70 | paper.fulltext.methods | tertiary care neonatal unit in Northern India |
Sequencing
22 runs over 22 samples · mean 2.18 Gbp per run (median 2.20 Gbp, total 47.96 Gbp; 22 runs with a base count) · layout PAIRED 22 · platform ILLUMINA 22 · models Illumina NovaSeq X Plus (22) · 95% of runs with a Sandpiper profile · first public 2025-08-12
Authors (5)
Devarajalu P first · Attri SV · Kumar J · Dutta S · Kabeerdoss J last
Downloads
PRJNA1304237.csv.gz (1.5 KB) · parquet (70.1 KB) — all 22 samples, every field with route and confidence · PRJNA1304237_determinations.csv.gz (1.2 KB) — 88 evidence rows