Gut microbiome in home vs hospital HCT (RCT)
202 stool samples from a Phase II randomized controlled trial at Duke University comparing home-based versus hospital-based hematopoietic stem cell transplantation, examining gut taxonomic diversity and antimicrobial resistance gene carriage. machine-written summary
202 samples · 202 runs · US · Age unknown · 2025 · 7.20 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,212 sample values (collection date, country, intervention, intervention detail, subject id, timepoint) |
| ✓ Abstract / description | 404 sample values (health condition, health condition detail) |
| ○ Full text | read; no usable statement or table · PMC12530115 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolved
28 of 28 people sampled more than once (202 samples; median 8, up to 13 per person). Schedule stated by the source: “serial stool at multiple timepoints incl. pre-transplant and day -7 to day 398 per patient” (time origin: transplant).
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 202 | 100% | 202 | |||
| health_condition | 202 | 100% | 202 | |||
| subject_id | 202 | 100% | 202 | |||
| collection_date | 202 | 100% | 202 | |||
| health_condition_detail | 202 | 100% | 202 | |||
| intervention | 202 | 100% | 202 | |||
| intervention_detail | 202 | 100% | 202 | |||
| timepoint_label | 202 | 100% | 202 |
- Duration of Hospitalization is Associated with the Gut Microbiome in Patients Undergoing Hematopoietic Stem Cell Transplantation: Early Results from a Randomized Trial of Home Versus Hospital Transplantation. 2025 PMID 41114048 PMC12530115 cites_accession
Archive description
Duration of Hospitalization is Associated with the Gut Microbiome in Patients Undergoing Hematopoietic Stem Cell Transplantation: Early Results from a Randomized Trial of Home Versus Hospital Transplantation
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.75. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host study.description · “Patients Undergoing Hematopoietic Stem Cell Transplantation”
- body site study.description · “Associated with the Gut Microbiome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN50622993 | collection_date | 2018 | R1 | 0.85 | biosample.attribute:collection_date | collection_date: 2018 |
| SAMN50622993 | country | US | R1 | 0.85 | biosample.attribute:geo_loc_name | geo_loc_name: USA: Durham, NC |
| SAMN50622993 | health_condition | transplant_or_immunocompromised | R4 | 0.50 | paper.abstract | Patients Undergoing Hematopoietic Stem Cell Transplantation |
| SAMN50622993 | health_condition_detail | patients undergoing hematopoietic stem cell transplantation (HCT) | R4 | 0.50 | paper.abstract | Patients Undergoing Hematopoietic Stem Cell Transplantation |
| SAMN50622993 | intervention | surgery | R1 | 0.80 | biosample.attribute:timepoint | timepoint: 15 |
| SAMN50622993 | intervention_detail | timepoint = 15 (after intervention start) | R1 | 0.80 | biosample.attribute:timepoint | timepoint: 15 |
| SAMN50622993 | subject_id | 17010 | R1 | 0.85 | biosample.attribute:patient | patient: 17010 |
| SAMN50622993 | timepoint_label | timepoint 15 | R1 | 0.85 | biosample.attribute:timepoint | timepoint: 15 |
Sequencing
202 runs over 202 samples · mean 7.39 Gbp per run (median 7.20 Gbp, total 1,492.01 Gbp; 202 runs with a base count) · layout PAIRED 202 · platform ILLUMINA 202 · models Illumina NovaSeq 6000 (202) · 0% of runs with a Sandpiper profile · first public 2025-08-21
Authors (0)
No author record.
Downloads
PRJNA1306109.csv.gz (6.7 KB) · parquet (78.8 KB) — all 202 samples, every field with route and confidence · PRJNA1306109_determinations.csv.gz (14.5 KB) — 1,616 evidence rows