Gut microbiota in alcoholic liver disease, Ningxia, China
56 fecal samples from adults with alcoholic liver disease in Ningxia, China, studied by 16S rRNA sequencing to characterize gut microbial composition across different disease states. machine-written summary
56 samples · 56 runs · CN · Adult · 2025 · 11.37 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 280 sample values (collection date, country, latitude, location region, longitude) |
| ✓ Abstract / description | 112 sample values (health condition, health condition detail) |
| ○ Full text | read; no usable statement or table · PMC13013527 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
design observational_with_procedure · FMT from healthy donors in ALD mouse model; human microbiome analysis
Genera, mean relative abundance over 56 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 56 | 100% | ||||
| country | 56 | 100% | 56 | |||
| health_condition | 56 | 100% | 56 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 56 | 100% | 56 | |||
| detailed_location | 56 | 100% | ||||
| health_condition_detail | 56 | 100% | 56 | |||
| latitude | 56 | 100% | 56 | |||
| location_region | 56 | 100% | 56 | |||
| longitude | 56 | 100% | 56 |
- Fecal microbiota transplantation ameliorates alcohol-associated liver disease through coordinated restoration of short-chain fatty acid and <i>α</i>-linolenic acid signaling. 2026 PMID 41889649 PMC13013527 own_data
Archive description
To investigate the manifestations of intestinal microecology in patients with alcoholic liver disease at different disease states.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.68. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site run.scientific_name · “human gut metagenome”
- body site study.description · “intestinal microecology in patients with alcoholic”
- life stage study.description · “patients with alcoholic liver disease”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN50712829 | collection_date | 2022-11-03 | R1 | 0.90 | biosample.attribute:collection_date | 2022-11-03 |
| SAMN50712829 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Ningxia |
| SAMN50712829 | health_condition | liver_disease | R4 | 0.50 | study.title | Microbial diversity in patients with alcoholic liver disease |
| SAMN50712829 | health_condition_detail | alcoholic liver disease at different disease states | R4 | 0.50 | study.description | intestinal microecology in patients with alcoholic liver disease at different disease states |
| SAMN50712829 | latitude | 38.4700 | R1 | 0.90 | biosample.attribute:lat_lon | 38.47 N 106.26 E |
| SAMN50712829 | location_region | Ningxia | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Ningxia |
| SAMN50712829 | longitude | 106.2600 | R1 | 0.90 | biosample.attribute:lat_lon | 38.47 N 106.26 E |
Sequencing
56 runs over 56 samples · mean 11.31 Gbp per run (median 11.37 Gbp, total 633.50 Gbp; 56 runs with a base count) · layout PAIRED 56 · platform ILLUMINA 56 · models Illumina MiSeq (56) · 100% of runs with a Sandpiper profile · first public 2025-12-14 – 2025-12-21
Authors (11)
Su R first · Ma J · Li J · Liu Y · Ma T · Wang J · Mai Q · Ma Q · Wang H · Yang S · Zhang X last
Downloads
PRJNA1308792.csv.gz (2.5 KB) · parquet (72.1 KB) — all 56 samples, every field with route and confidence · PRJNA1308792_determinations.csv.gz (3.4 KB) — 392 evidence rows