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PRJNA1309965 SRP611895

Gut microbes, fecal microplastics, healthy adults, Shanghai

Lactiplantibacillus plantarum from healthy adult feces functions as a natural defense against microplastic toxicity

Cross-sectional study of 138 fecal samples from healthy adults in Shanghai, China, examining the correlation between fecal microplastics and gut microbiota, including Lactiplantibacillus plantarum. machine-written summary

138 samples · 138 runs · CN · Adult · 2025 · 6.51 Gbp / sample

Sources
✓Sequence archive 690✓Abstract / description 276–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive690 sample values (collection date, country, latitude, location region, longitude)
✓ Abstract / description276 sample values (health condition, subject id)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult138
Condition
healthy_control138
Country
CN138
Body site
primary138
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 137 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.51 Gbp per sample0130Gbp
Community composition
Faecalibacterium 11.4%Roseburia 8.2%Blautia_A 7.3%Bacteroides 5.2%Bifidobacterium 4.0%Phocaeicola 3.7%Ruminococcoides 3.2%Mediterraneibacter 3.1%Fimenecus 2.4%Gemmiger 2.4%Anaerostipes 2.3%Fusicatenibacter 2.2%not assigned to a genus 4.1%other genera 40.6%

Genera, mean relative abundance over 137 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category138 100%
country138 100%138
health_condition138 100%138
subject_id138 100%138
collection_date138 100%138
detailed_location138 100%
latitude138 100%138
location_region138 100%138
longitude138 100%138
Details
Archive description

Emerging evidence highlights the detrimental health impacts of microplastics (MPs) exposure, with the gut microbiota playing a critical role in modulating these effects. However, effective approach to mitigate MPs toxicity based on gut microbiome changes has not yet been developed. Here, a cross-sectional study involving 138 individuals revealed a correlation between fecal MPs and gut microbiota.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.62. Assay shotgun_dna.

  • host study.title · “healthy adult feces”
  • body site sample.attr.isolation_source · “feces (n=138/138)”
  • life stage study.title · “healthy adult feces”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN50761855collection_date2024-04-23R10.90biosample.attribute:collection_date2024-04-23
SAMN50761855countryCNR10.90sample.attr.geo_loc_nameChina:Shanghai
SAMN50761855health_conditionhealthy_controlR40.50study.titlehealthy adult feces
SAMN50761855latitude31.4100R10.90biosample.attribute:lat_lon31.41 N 120.53 E
SAMN50761855location_regionShanghaiR10.85biosample.attribute:geo_loc_nameChina:Shanghai
SAMN50761855longitude120.5300R10.90biosample.attribute:lat_lon31.41 N 120.53 E
SAMN50761855subject_idSAMN50761855R40.60design.one_sample_per_subject:descriptiona cross-sectional study involving 138 individuals revealed a correlation between fecal MPs and gut microbiota
Sequencing

138 runs over 138 samples · mean 6.64 Gbp per run (median 6.51 Gbp, total 915.85 Gbp; 138 runs with a base count) · layout PAIRED 138 · platform ILLUMINA 138 · models Illumina NovaSeq 6000 (138) · 99% of runs with a Sandpiper profile · first public 2025-08-27

Authors (0)

No author record.

Downloads

PRJNA1309965.csv.gz (4.3 KB) · parquet (75.9 KB) — all 138 samples, every field with route and confidence · PRJNA1309965_determinations.csv.gz (6.0 KB) — 966 evidence rows

Samples (138 · every field this project has values for · hover a cell for its source)
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