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PRJNA1317556 SRP617652

Small intestine microbiome/metabolome in ACLF, China

Microbiome and metabolome characteristics of the small intestine in patients with ACLF

80 samples from Chongqing, China, characterizing small intestine microbiome and metabolome features in patients with acute-on-chronic liver failure (ACLF). machine-written summary

80 samples · 80 runs · CN · Age unknown · 2025 · 12.91 Gbp / sample

Sources
✓Sequence archive 400–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive400 sample values (collection date, country, health condition, health condition detail, location locality)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown80
Condition
liver_disease80
Country
CN80
Body site
primary80
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 38 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 42 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 12.91 Gbp per sample0130Gbp
Community composition
Bacteroides 10.8%Enterococcus_B 8.1%Blautia_A 7.4%Escherichia 6.4%Phocaeicola 6.0%Streptococcus 5.8%Roseburia 4.9%Bifidobacterium 3.8%Faecalibacterium 2.9%Veillonella 2.0%Parabacteroides 2.0%Ruminococcoides 1.7%not assigned to a genus 6.5%other genera 31.9%

Genera, mean relative abundance over 42 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country80 100%80
health_condition80 100%80
subject_id0 0%
collection_date80 100%80
detailed_location80 100%
health_condition_detail80 100%80
location_locality80 100%80
Details
Archive description

Microbiome and metabolome characteristics of the small intestine in patients with ACLF

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • host run.scientific_name · “human gut metagenome”
  • body site study.title · “microbiome and metabolome characteristics of the small intestine”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN51145475collection_date2022-02-03R10.90biosample.attribute:collection_date2022-02-03
SAMN51145475countryCNR10.90sample.attr.geo_loc_nameChina:Chongqing
SAMN51145475health_conditionliver_diseaseR10.70sample.name_rule:aliasalias: ALD.RE.1
SAMN51145475health_condition_detailACLF due to alcoholic liver disease (ALD)R10.70sample.name_rule:aliasalias: ALD.RE.1
SAMN51145475location_localityChongqingR10.85biosample.attribute:geo_loc_nameChina:Chongqing
Sequencing

80 runs over 80 samples · mean 10.84 Gbp per run (median 12.91 Gbp, total 867.48 Gbp; 80 runs with a base count) · layout PAIRED 80 · platform ILLUMINA 80 · models Illumina NovaSeq 6000 (80) · 95% of runs with a Sandpiper profile · first public 2025-09-05 – 2025-09-21

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA1317556.csv.gz (2.9 KB) · parquet (73.0 KB) — all 80 samples, every field with route and confidence · PRJNA1317556_determinations.csv.gz (4.3 KB) — 400 evidence rows

Samples (80 · every field this project has values for · hover a cell for its source)
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