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PRJNA1333319 SRP625475

Phage-bacteria networks in colitis, colorectal cancer

Phage bacteria interaction networks differentiate ulcerative colitis and colorectal cancer from the healthy gut

Gut metagenome study of 27 samples examining phage-bacteria interaction networks to differentiate ulcerative colitis and colorectal cancer from healthy guts; no further details on population, location, or design given. machine-written summary

27 samples · 27 runs · DE · Age unknown · 2026 · 2.31 Gbp / sample

Sources
✓Sequence archive 72–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive72 sample values (collection date, country, health condition, health condition detail)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown27
Condition
colorectal_cancer3
healthy_control3
ulcerative_colitis3
Country
DE27
Body site
primary27
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 26 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 2.31 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country27 100%27
health_condition9 33%9
subject_id0 0%
collection_date27 100%27
health_condition_detail9 33%9
Details
Archive description

Phage bacteria interactions are increasingly recognized as key drivers of gut microbiome changes in IBD and CRC. Using viral tagging, we found expanded and more complex phage host networks in UC and CRC compared to healthy controls. These results suggest condition-specific interactions that may shape gut dysbiosis in inflammatory and neoplastic diseases.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “differentiate ulcerative colitis and colorectal cancer from the healthy gut”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN51786424collection_date2023-08-01R10.85biosample.attribute:collection_datecollection_date: 2023-08-01
SAMN51786424countryDER10.85biosample.attribute:geo_loc_namegeo_loc_name: Germany
SAMN51786451health_conditionhealthy_controlR10.85biosample.attribute:titletitle: H_virome
SAMN51786451health_condition_detailH_viromeR10.85biosample.attribute:titletitle: H_virome
Sequencing

27 runs over 27 samples · mean 2.36 Gbp per run (median 2.31 Gbp, total 63.65 Gbp; 27 runs with a base count) · layout PAIRED 27 · platform ILLUMINA 27 · models Illumina NovaSeq 6000 (27) · 0% of runs with a Sandpiper profile · first public 2026-01-02 – 2026-01-20

Authors (0)

No author record.

Downloads

PRJNA1333319.csv.gz (1.6 KB) · parquet (70.0 KB) — all 27 samples, every field with route and confidence · PRJNA1333319_determinations.csv.gz (1.2 KB) — 72 evidence rows

Samples (27 · every field this project has values for · hover a cell for its source)
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