Mother-infant fecal metagenomes in HIV/HBV-affected cohort
191 fecal metagenome samples from a longitudinal cohort of mothers (healthy, HIV-infected, or HBV-infected) and their infants, sampled at birth, 1 month, and 3 months. machine-written summary
191 samples · 191 runs · CN · Infant / toddler · 2026 · 7.52 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 929 sample values (collection date, country, health condition, health condition detail, sex, subject id, timepoint) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinalmother–infant — not resolved
43 of 66 people sampled more than once (113 samples; median 3, up to 3 per person) · follow-up median 3 mo (max 5 mo) · median interval between samples 47 d (time from collection dates). Schedule stated by the source: “Infants sampled at birth, 1 month, and 3 months; mothers sampled (timing not specified beyond cohort description).” (time origin: birth).
Each row is one person (36 shown of 43); dots are samples at days since that person's first sample.
117 subjects comprising mothers (healthy/HIV+/HBV+) and their infants, i.e. mother-infant pairs/dyads..
Genera, mean relative abundance over 136 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 191 | 100% | 191 | |||
| health_condition | 85 | 45% | 85 | |||
| subject_id | 187 | 98% | 187 | |||
| collection_date | 190 | 99% | 190 | |||
| timepoint_label | 140 | 73% | 140 | |||
| health_condition_detail | 85 | 45% | 85 | |||
| sex | 51 | 27% | 51 |
Archive description
This study encompasses a cohort with diverse maternal conditions, including healthy mothers, with HIV infection, and with HBV infection. Metagenomic data are available from fecal samples of these mothers. For infants, longitudinal metagenomic data from fecal samples are available during early life (at birth, 1 month, and 3 months).
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and infant / toddler and neonate by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host study.title · “mother-infant fecal samples”
- body site study.title · “mother-infant fecal samples”
- life stage study.description · “at birth, 1 month, and 3 months”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN53362469 | collection_date | 2023-01-20 | R1 | 0.85 | biosample.attribute:collection_date | 2023-01-20 |
| SAMN53362469 | country | CN | R1 | 0.90 | biosample_attr | China |
| SAMN53362469 | health_condition | other_infection | R1 | 0.70 | sample.name_rule:library_name | MoHIV |
| SAMN53362469 | health_condition_detail | MoHIV | R1 | 0.70 | sample.name_rule:library_name | MoHIV |
| SAMN53362469 | sex | female | R1 | 0.70 | sample.name_rule:library_name | Mo |
| SAMN53362469 | subject_id | MoHIV_1 | R1 | 0.70 | sample.name_rule:library_name | MoHIV_1 |
| SAMN53362520 | timepoint_label | birth | R1 | 0.70 | sample.name_rule:library_name | 1 |
Sequencing
191 runs over 191 samples · mean 8.36 Gbp per run (median 7.52 Gbp, total 1,597.14 Gbp; 191 runs with a base count) · layout PAIRED 191 · platform ILLUMINA 191 · models Illumina NovaSeq X Plus (191) · 98% of runs with a Sandpiper profile · first public 2026-01-23
Authors (0)
No author record.
Help complete this project
2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata
Downloads
PRJNA1368374.csv.gz (7.1 KB) · parquet (79.8 KB) — all 191 samples, every field with route and confidence · PRJNA1368374_determinations.csv.gz (8.2 KB) — 929 evidence rows