Fecal microbiome in keratoconus patients, Bogotá, Colombia
Cross-sectional study of 44 fecal samples from children, adolescents and adults in Bogotá, Colombia, comparing patients with keratoconus and healthy controls. machine-written summary
44 samples · 44 runs · CO · Age unknown · 2025 · 4.70 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 440 sample values (age, collection date, country, health condition, health condition detail, latitude, location locality, location region) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 44 | 100% | ||||
| country | 44 | 100% | 44 | |||
| health_condition | 44 | 100% | 44 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 44 | 100% | 44 | |||
| collection_date | 44 | 100% | 44 | |||
| detailed_location | 44 | 100% | ||||
| health_condition_detail | 44 | 100% | 44 | |||
| latitude | 44 | 100% | 44 | |||
| location_locality | 44 | 100% | 44 | |||
| location_region | 44 | 100% | 44 | |||
| longitude | 44 | 100% | 44 | |||
| sex | 44 | 100% | 44 |
Archive description
This is an exploratory observational study that characterizes the fecal microbiome of Colombian patients with keratoconus using whole metagenomic sequencing.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adolescent and adult and child by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host run.scientific_name · “human metagenome”
- body site study.description · “fecal microbiome of Colombian patients”
- life stage sample.attr.host_age · “14 (n=19/44)”
- life stage sample.attr.host_age · “22 (n=14/44)”
- life stage sample.attr.host_age · “7 (n=5/44)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN53694452 | age_at_collection_days | 8035.5 | R1 | 0.85 | sample.attr.host_age | 22 |
| SAMN53694452 | collection_date | 2024-06-13 | R1 | 0.90 | biosample.attribute:collection_date | 2024-06-13 |
| SAMN53694452 | country | CO | R1 | 0.90 | sample.attr.geo_loc_name | Colombia:Bogota |
| SAMN53694452 | health_condition | other_disease | R1 | 0.90 | biosample_attr | Keratoconus |
| SAMN53694452 | health_condition_detail | Keratoconus | R1 | 0.90 | sample.attr.host_disease | Keratoconus |
| SAMN53694452 | latitude | 4.6097 | R1 | 0.90 | biosample.attribute:lat_lon | 4.60971 N 74.08175 W |
| SAMN53694452 | location_locality | Bogotá | R1 | 0.85 | biosample.attribute:geo_loc_name | Colombia:Bogota |
| SAMN53694452 | location_region | Bogota D.C. | R1 | 0.60 | biosample.attribute:lat_lon | 4.60971 N 74.08175 W |
| SAMN53694452 | longitude | -74.0817 | R1 | 0.90 | biosample.attribute:lat_lon | 4.60971 N 74.08175 W |
| SAMN53694452 | sex | male | R1 | 0.90 | sample.attr.host_sex | male |
Sequencing
44 runs over 44 samples · mean 4.72 Gbp per run (median 4.70 Gbp, total 207.64 Gbp; 44 runs with a base count) · layout PAIRED 44 · platform DNBSEQ 44 · models DNBSEQ-G400 (44) · 0% of runs with a Sandpiper profile · first public 2025-12-21
Authors (0)
No author record.
Downloads
PRJNA1374193.csv.gz (2.3 KB) · parquet (72.3 KB) — all 44 samples, every field with route and confidence · PRJNA1374193_determinations.csv.gz (3.5 KB) — 440 evidence rows