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PRJNA1401743 SRP727969

Microbiome in Crohn's disease before/after FMT, Hong Kong

Fecal microbiome in Crohn's disease before and after FMT

57 fecal shotgun metagenome samples from Crohn's disease patients in Hong Kong, collected before and after fecal microbiota transplantation (FMT) in a longitudinal design to characterize microbiome changes. machine-written summary

57 samples · 57 runs · HK · Age unknown · 2026 · 7.90 Gbp / sample

Sources
✓Sequence archive 473✓Abstract / description 4–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive473 sample values (country, health condition, health condition detail, intervention, latitude, location region, longitude, subject id)
✓ Abstract / description4 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Faecal microbiota transplantation design single_arm_before_after · population crohns_disease · FMT in Crohn's disease patients, before/after sampling

“before and after FMT to characterize fecal microbiome changes” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
unknown57
Condition
crohns_disease57
Country
HK57
Body site
primary57
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 56 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.90 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

25 of 30 people sampled more than once (50 samples; median 2, up to 2 per person).

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country57 100%57
health_condition57 100%552
subject_id55 96%55
detailed_location57 100%
health_condition_detail57 100%552
latitude57 100%57
location_region57 100%57
longitude57 100%57
timepoint_label55 96%55
intervention25 44%25
Details
Archive description

Shotgun metagenomic sequencing of fecal samples from patients with Crohn's disease before and after FMT to characterize fecal microbiome changes.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.82. Assay shotgun_dna.

  • host run.scientific_name · “human gut metagenome”
  • body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN62396082countryHKR10.90sample.attr.geo_loc_nameHong Kong
SAMN62396082health_conditioncrohns_diseaseR10.70sample.name_rule:aliasB001
SAMN62396112health_conditioncrohns_diseaseR40.50study.descriptionpatients with Crohn's disease
SAMN62396082health_condition_detailB001R10.70sample.name_rule:aliasB001
SAMN62396112health_condition_detailCrohn's diseaseR40.50study.descriptionpatients with Crohn's disease
SAMN62396114interventionfmtR10.70sample.name_rule:aliasF003
SAMN62396082latitude22.3800R10.90biosample.attribute:lat_lon22.38 N 114.19 E
SAMN62396082location_regionSha TinR10.60biosample.attribute:lat_lon22.38 N 114.19 E
SAMN62396082longitude114.1900R10.90biosample.attribute:lat_lon22.38 N 114.19 E
SAMN62396082subject_id001R10.70sample.name_rule:aliasB001
SAMN62396082timepoint_labelbefore FMTR10.70sample.name_rule:aliasB001
Sequencing

57 runs over 57 samples · mean 7.67 Gbp per run (median 7.90 Gbp, total 437.40 Gbp; 57 runs with a base count) · layout PAIRED 57 · platform ILLUMINA 57 · models Illumina NovaSeq 6000 (57) · 0% of runs with a Sandpiper profile · first public 2026-08-20

Authors (0)

No author record.

Downloads

PRJNA1401743.csv.gz (2.5 KB) · parquet (72.2 KB) — all 57 samples, every field with route and confidence · PRJNA1401743_determinations.csv.gz (4.4 KB) — 477 evidence rows

Samples (57 · every field this project has values for · hover a cell for its source)
Loading the sample table…