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PRJNA1403004 SRP662258

Infant gut metagenomes from the CHILD Cohort Study

Shotgun metagenomic sequencing of infant stool samples from the CHILD Cohort Study

Shotgun metagenomic sequencing of 1018 stool samples from infants in the CHILD Cohort Study, a longitudinal cohort investigating early-life gut microbiota; no specific health condition or location is specified in the available sources. machine-written summary

1,018 samples · 1,018 runs · CA · Infant / toddler · 2026 · 0.94 Gbp / sample

Sources
✓Sequence archive 1,018○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,018 sample values (country)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown1,018
Country
CA1,018
Body site
primary1,018
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 8 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 42 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 66 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 455 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 445 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 2 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.94 Gbp per sample0130Gbp
Community composition
Bifidobacterium 38.7%Blautia_A 8.5%Mediterraneibacter 7.1%Escherichia 3.6%Streptococcus 3.5%Bacteroides 2.7%Faecalibacterium 2.0%Anaerostipes 2.0%Collinsella 1.8%Phocaeicola 1.5%Fusicatenibacter 1.4%Roseburia 1.3%not assigned to a genus 5.9%other genera 19.9%

Genera, mean relative abundance over 963 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country1,018 100%1,018
health_condition0 0%
subject_id0 0%
Papers (1)
  • Infant gut microbiomes contribute to metabolic states that impact brain function curated
Details
Archive description

This project contains shotgun metagenomic sequencing data generated from stool samples collected as part of the CHILD Cohort Study to investigate early-life gut microbiota and health outcomes.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler and child by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site study.title · “sequencing of infant stool samples from the”
  • body site study.description · “data generated from stool samples collected as”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.title · “metagenomic sequencing of infant stool samples from”
  • life stage study.title · “samples from the CHILD Cohort Study”
  • life stage study.description · “part of the CHILD Cohort Study to”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN54614884countryCAR10.90biosample_attrCanada: Alberta, Edmonton
Sequencing

1,018 runs over 1,018 samples · mean 0.94 Gbp per run (median 0.94 Gbp, total 958.64 Gbp; 1,018 runs with a base count) · layout PAIRED 1,018 · platform ILLUMINA 1,018 · models Illumina NovaSeq X (1,018) · 95% of runs with a Sandpiper profile · first public 2026-01-16 – 2026-01-17

Authors (29)

Midani FS first · Lee D · Moon Y · Seale M · Horvath TD · Ardis AK · Cantú J · Coles E · Pizzini JD · Zhu D · Dooling SW · Ahern GJ · Ardis CK · Beckford A · Ruggiero NM · Shin J · Joos R · Stanton C · Ross RP · Dai DL · Mandhane PJ · Petersen C · Turvey SE · Kiely ME · Murray DM · Costa-Mattioli M · Tolias KF · Britton RA · Danhof HA last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA1403004.csv.gz (24.6 KB) · parquet (111.0 KB) — all 1,018 samples, every field with route and confidence · PRJNA1403004_determinations.csv.gz (3.4 KB) — 1,018 evidence rows

Samples (1,018 · every field this project has values for · hover a cell for its source)
Loading the sample table…