Bifidobacterium probiotic & gut microbiota during travel
80 fecal samples from healthy adults in a randomized, double-blind, placebo-controlled trial testing multi-strain Bifidobacterium probiotic supplementation on gut microbiota stability during a short trip from China to Japan. machine-written summary
80 samples · 80 runs · CN · Adult · 2026 · 10.61 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 560 sample values (collection date, country, intervention, latitude, longitude, subject id, timepoint) |
| ✓ Abstract / description | 160 sample values (health condition, health condition detail) |
| ○ Full text | read; no usable statement or table · PMC12935942 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention · arms resolved
Probiotic (live microorganisms; single strain or mixture) design randomized_controlled_trial · population healthy_control · Multi-strain Bifidobacterium probiotic vs placebo during 5-day travel
“randomized, double-blind, placebo-controlled study” — abstract:41769651 (study level; per-sample arms are in the intervention column below)
longitudinal
2 of 2 people sampled more than once (80 samples; median 40, up to 44 per person) · follow-up median 5 d (max 5 d) · median interval between samples 5 d (time from visit codes mapped to the stated schedule). Schedule stated by the source: “stool collected before departure (Day 0) and after return (Day 5)” (time origin: baseline); stated follow-up 5 d.
Each row is one person (2 shown); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 79 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 80 | 100% | ||||
| country | 80 | 100% | 80 | |||
| health_condition | 80 | 100% | 80 | |||
| subject_id | 80 | 100% | 80 | |||
| collection_date | 80 | 100% | 80 | |||
| health_condition_detail | 80 | 100% | 80 | |||
| intervention | 80 | 100% | 80 | |||
| latitude | 80 | 100% | 80 | |||
| longitude | 80 | 100% | 80 | |||
| timepoint_label | 80 | 100% | 80 |
- <i>Bifidobacterium</i> supplementation maintains gut microbiota stability and enhances well-being during short-term travel. 2026 PMID 41769651 PMC12935942 own_data
Archive description
We analyzed data of gastrointestinal microbiota in feces collected from the subjects
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Data of Feces Analyzed by Metagenomics”
- body site study.description · “analyzed data of gastrointestinal microbiota in feces”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN54995908 | collection_date | 2025-05-31/2025-06-05 | R1 | 0.90 | biosample.attribute:collection_date | 2025-05-31/2025-06-05 |
| SAMN54995908 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China |
| SAMN54995908 | health_condition | healthy_control | R4 | 0.50 | paper.abstract | Forty healthy adults were randomly assigned |
| SAMN54995908 | health_condition_detail | healthy adults receiving probiotic or placebo intervention | R4 | 0.50 | paper.abstract | Forty healthy adults |
| SAMN54995908 | intervention | probiotic | R1 | 0.70 | sample.name_rule:library_name | PRO_BEF_1 |
| SAMN54995908 | latitude | 31.0000 | R1 | 0.90 | biosample.attribute:lat_lon | 31 N 121 E |
| SAMN54995908 | longitude | 121.0000 | R1 | 0.90 | biosample.attribute:lat_lon | 31 N 121 E |
| SAMN54995908 | subject_id | PRO | R1 | 0.70 | sample.name_rule:library_name | PRO_BEF_1 |
| SAMN54995908 | timepoint_label | before | R1 | 0.70 | sample.name_rule:library_name | PRO_BEF_1 |
Sequencing
80 runs over 80 samples · mean 10.98 Gbp per run (median 10.61 Gbp, total 878.17 Gbp; 80 runs with a base count) · layout PAIRED 80 · platform ILLUMINA 80 · models Illumina NovaSeq 6000 (80) · 99% of runs with a Sandpiper profile · first public 2026-02-10
Authors (12)
Wang L first · Yu Y · Shen X · Li X · Wang D · Zhai Y · Jiang W · Zhao W · Yu Q · Liong MT · Chen D · Zhao A last
Downloads
PRJNA1417478.csv.gz (2.7 KB) · parquet (73.4 KB) — all 80 samples, every field with route and confidence · PRJNA1417478_determinations.csv.gz (5.5 KB) — 720 evidence rows