Home › Studies › PRJNA1430171
PRJNA1430171 SRP680450

Gut metagenomes of adults with type 2 diabetes, Kanazawa

Metagenome sequencing for persons treated with antidiabetic drug

32 gut metagenome samples from adults with type 2 diabetes in Kanazawa, Japan, treated with an antidiabetic drug; no further design details are given. machine-written summary

32 samples · 32 runs · JP · Adult · 2026 · 0.66 Gbp / sample

Sources
✓Sequence archive 224✓Abstract / description 64–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive224 sample values (collection date, country, latitude, location locality, longitude, subject id, timepoint)
✓ Abstract / description64 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult32
Condition
type2_diabetes32
Country
JP32
Body site
primary32
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 31 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 1 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.66 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

16 of 16 people sampled more than once (32 samples; median 2, up to 2 per person) · follow-up median 12 mo (max 12 mo) · median interval between samples 12 mo (time from timepoint labels). Schedule stated by the source: “Samples collected at day 0 and month 12 for subjects treated with antidiabetic drug” (time origin: intervention_start); stated follow-up 12 mo.

1111: day 011: day 3651212: day 012: day 3651313: day 013: day 3651414: day 014: day 3651515: day 015: day 211616: day 016: day 3651717: day 017: day 3651818: day 018: day 3651919: day 019: day 3652020: day 020: day 3652121: day 021: day 3652222: day 022: day 3652323: day 023: day 36544: day 04: day 36555: day 05: day 36599: day 09: day 280 d3 mo6 mo9 mo12 mo

Each row is one person (16 shown); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition
Blautia_A 22.0%Bifidobacterium 18.4%Ruminococcoides 9.1%Streptococcus 9.0%Fusicatenibacter 7.9%Eggerthella 2.7%Veillonella_A 2.7%Eubacterium_R 2.5%Eubacterium_I 2.0%Faecalimonas 1.5%Mediterraneibacter 1.3%Clostridium_A 1.2%not assigned to a genus 9.8%other genera 9.8%

Genera, mean relative abundance over 1 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category32 100%
country32 100%32
health_condition32 100%32
subject_id32 100%32
collection_date32 100%32
detailed_location32 100%
health_condition_detail32 100%32
latitude32 100%32
location_locality32 100%32
longitude32 100%32
timepoint_label32 100%32
Details
Archive description

Metagenome sequencing for persons treated with antidiabetic drug

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site external_curation.infant_catalog · “body_site_call gut”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN56268739collection_date2021-07-30R10.90biosample.attribute:collection_date2021-07-30
SAMN56268739countryJPR10.90sample.attr.geo_loc_nameJapan: Kanazawa
SAMN56268739health_conditiontype2_diabetesR40.50study.descriptionpersons treated with antidiabetic drug
SAMN56268739health_condition_detailAntidiabetic drug treatment; likely type 2 diabetes or prediabetesR40.50study.descriptionpersons treated with antidiabetic drug
SAMN56268739latitude36.5500R10.90biosample.attribute:lat_lon36.55 N 136.67 E
SAMN56268739location_localityKanazawaR10.85biosample.attribute:geo_loc_nameJapan: Kanazawa
SAMN56268739longitude136.6700R10.90biosample.attribute:lat_lon36.55 N 136.67 E
SAMN56268739subject_id4R10.70sample.name_rule:source_material_idSG4D0
SAMN56268739timepoint_labelday 0R10.70sample.name_rule:source_material_idSG4D0
Sequencing

32 runs over 32 samples · mean 0.67 Gbp per run (median 0.66 Gbp, total 21.52 Gbp; 32 runs with a base count) · layout PAIRED 32 · platform ILLUMINA 32 · models Illumina MiSeq (32) · 3% of runs with a Sandpiper profile · first public 2026-03-08

Authors (0)

No author record.

Downloads

PRJNA1430171.csv.gz (1.8 KB) · parquet (71.4 KB) — all 32 samples, every field with route and confidence · PRJNA1430171_determinations.csv.gz (2.6 KB) — 288 evidence rows

Samples (32 · every field this project has values for · hover a cell for its source)
Loading the sample table…