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PRJNA1436979 SRP683497

Fecal metagenomics in Normal, MPEI, SPEI groups, China

Shotgun metagenomic profiling of fecal microbiota in Normal, MPEI, and SPEI subjects

Case-control study of 50 fecal samples from China comparing gut microbiota across Normal, MPEI, and SPEI groups using shotgun metagenomic sequencing. machine-written summary

50 samples · 50 runs · CN · Age unknown · 2026 · 8.80 Gbp / sample

Sources
✓Sequence archive 100✓Abstract / description 50–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive100 sample values (collection date, country)
✓ Abstract / description50 sample values (health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown50
Country
CN50
Body site
primary50
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 49 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 8.80 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country50 100%50
health_condition0 0%
subject_id0 0%
collection_date50 100%50
health_condition_detail50 100%50
Details
Archive description

This project investigated gut microbial alterations in human fecal samples from Normal, MPEI, and SPEI groups using shotgun metagenomic sequencing. Total DNA was extracted from stool samples, paired-end libraries were prepared, and sequencing was performed on the Illumina NovaSeq X Plus platform.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.72. Assay shotgun_dna.

  • host study.description · “human fecal samples from Normal, MPEI, and SPEI groups”
  • body site study.description · “Total DNA was extracted from stool samples”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN56491314collection_date2024R10.90biosample.attribute:collection_date2024
SAMN56491314countryCNR10.90sample.attr.geo_loc_nameChina
SAMN56491314health_condition_detailmixed_case_control: Normal vs MPEI vs SPEI groupsR40.40study.titleNormal, MPEI, and SPEI subjects
Sequencing

50 runs over 50 samples · mean 8.75 Gbp per run (median 8.80 Gbp, total 437.37 Gbp; 50 runs with a base count) · layout PAIRED 50 · platform ILLUMINA 50 · models Illumina NovaSeq X Plus (50) · 0% of runs with a Sandpiper profile · first public 2026-03-17

Authors (0)

No author record.

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA1436979.csv.gz (2.1 KB) · parquet (70.5 KB) — all 50 samples, every field with route and confidence · PRJNA1436979_determinations.csv.gz (1.2 KB) — 150 evidence rows

Samples (50 · every field this project has values for · hover a cell for its source)
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