Infant gut microbiome in allergic proctocolitis cohort
740 samples from a longitudinal cohort study investigating early-life gut microbiome development and its association with pediatric allergic diseases, including allergic proctocolitis. machine-written summary
740 samples · 740 runs · US · Infant / toddler · 2026 · 3.67 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,480 sample values (collection date, country) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC13127034 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 740 | 100% | 740 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% | ||||
| collection_date | 740 | 100% | 740 |
- Strain-level microbial signatures and inferred functional alterations in infants with food protein-induced allergic proctocolitis. PMID 42010622 PMC13127034 curated
Archive description
A prospective observational study designed to investigate the development of the early-life gut microbiome and its association with pediatric allergic diseases
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler and child by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage verdict include”
- body site study.title · “Infant gut microbiome samples Gastrointestinal”
- body site study.description · “of the early-life gut microbiome and its”
- life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
- life stage study.title · “Infant gut microbiome samples”
- life stage study.description · “its association with pediatric allergic diseases”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN56802466 | collection_date | 2014-07-01 | R1 | 0.85 | biosample.attribute:collection_date | collection_date: 2014-07-01 |
| SAMN56802466 | country | US | R1 | 0.90 | biosample_attr | USA: Massachusetts, Boston |
Sequencing
740 runs over 740 samples · mean 3.74 Gbp per run (median 3.67 Gbp, total 2,765.73 Gbp; 740 runs with a base count) · layout PAIRED 740 · platform ILLUMINA 740 · models NextSeq 500 (740) · 0% of runs with a Sandpiper profile · first public 2026-04-05 – 2026-04-12
Authors (9)
Goldstein C first · Lavy I · Sun T · Ennis D · Shreffler WG · Yuan Q · Virkud YV · Martin VM · Yassour M last
Help complete this project
3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata
Downloads
PRJNA1445880.csv.gz (19.7 KB) · parquet (100.0 KB) — all 740 samples, every field with route and confidence · PRJNA1445880_determinations.csv.gz (9.2 KB) — 1,480 evidence rows