FMT for Ulcerative Colitis in Bai Donors, Yunnan, China
387 samples from an intervention study of fecal microbiota transplantation (FMT) for ulcerative colitis in Bai ethnic group participants in Yunnan, China, using non-urbanized donors and multi-omic sequencing. machine-written summary
387 samples · 387 runs · CN · Age unknown · 2026 · 9.81 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 2,409 sample values (collection date, country, health condition, health condition detail, location region, subject id, timepoint) |
| – Abstract / description | no abstract or project description |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Faecal microbiota transplantation design single_arm_before_after · population ulcerative_colitis · FMT from non-urbanized donors for ulcerative colitis treatment
“Fecal Microbiota Transplantation for Ulcerative Colitis with Non-urbanized Donors” — study.title (study level; per-sample arms are in the intervention column below)
longitudinal — not resolvedFMT donor → recipient — not resolved
100 of 109 people sampled more than once (378 samples; median 4, up to 15 per person). Schedule stated by the source: “Repeated fecal sampling of UC patients before and after FMT intervention; exact day offsets not stated in provided metadata.”.
FMT study: UC patient recipients received stool from non-urbanized donors; exact donor-recipient pairing counts not given in metadata..
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 387 | 100% | 387 | |||
| health_condition | 387 | 100% | 387 | |||
| subject_id | 387 | 100% | 387 | |||
| collection_date | 387 | 100% | 387 | |||
| detailed_location | 387 | 100% | ||||
| health_condition_detail | 387 | 100% | 387 | |||
| location_region | 387 | 100% | 387 | |||
| timepoint_label | 87 | 22% | 87 |
Archive description
This BioProject encompasses a comprehensive multi-omic study of a fecal microbiota transplantation (FMT) treatment cohort comprising Bai ethnic group participants. The study integrates three complementary sequencing datasets to investigate the dynamics of gut microbiota and host mucosal responses during FMT therapy: 1) Fecal whole-metagenome shotgun sequencing, to profile the composition, functional potential, and temporal changes of the luminal gut microbiome 2) Intestinal mucosal 16S rRNA gene amplicon sequencing, to characterize the mucosa-associated microbial community and its response to FMT 3) Intestinal mucosal RNA sequencing (transcriptomics), to assess host gene expression changes in the intestinal epithelium and elucidate host-microbiota interactions underlying FMT efficacy. This multi-omic resource aims to advance our understanding of FMT-mediated gut microbiome modulation and host-microbe crosstalk in a distinct ethnic population, providing a foundational dataset for future translational research on FMT therapies.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.75. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host study.description · “Bai ethnic group participants”
- body site study.description · “Fecal whole-metagenome shotgun sequencing”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN57172608 | collection_date | 2022-10/2025-10 | R1 | 0.90 | biosample.attribute:collection_date | 2022-10/2025-10 |
| SAMN57172608 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:Yunnan |
| SAMN57172608 | health_condition | ulcerative_colitis | R1 | 0.70 | sample.name_rule:alias | 002UC0 |
| SAMN57172608 | health_condition_detail | UC | R1 | 0.70 | sample.name_rule:alias | 002UC0 |
| SAMN57172608 | location_region | Yunnan | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Yunnan |
| SAMN57172608 | subject_id | 002 | R1 | 0.70 | sample.name_rule:alias | 002UC0 |
| SAMN57172608 | timepoint_label | baseline | R1 | 0.70 | sample.name_rule:alias | 002UC0 |
Sequencing
387 runs over 387 samples · mean 10.19 Gbp per run (median 9.81 Gbp, total 3,944.68 Gbp; 387 runs with a base count) · layout PAIRED 387 · platform ILLUMINA 387 · models Illumina NovaSeq 6000 (387) · 0% of runs with a Sandpiper profile · first public 2026-04-24 – 2026-04-29
Authors (0)
No author record.
Downloads
PRJNA1450848.csv.gz (9.8 KB) · parquet (83.1 KB) — all 387 samples, every field with route and confidence · PRJNA1450848_determinations.csv.gz (19.1 KB) — 2,409 evidence rows