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PRJNA1457655 SRP695440

Gut Microbiome in Middle-Aged Runners vs Sedentary Controls

Functional Signatures of the Gut Microbiome in Middle-Aged Regular Runners: Insights from a Metagenomic Study

Cross-sectional shotgun metagenomic study of 66 fecal samples from middle-aged regular runners and sedentary controls, comparing gut microbiota taxonomy, metabolic pathways, antibiotic resistance, and virulence factors. machine-written summary

66 samples · 66 runs · CN · Adult · 2026 · 10.72 Gbp / sample

Sources
✓Sequence archive 264○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive264 sample values (country, latitude, location locality, longitude)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC13395746
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult66
Country
CN66
Body site
primary66
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 2 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 64 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.72 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category66 100%
country66 100%66
health_condition0 0%
subject_id0 0%
detailed_location66 100%
latitude66 100%66
location_locality66 100%66
longitude66 100%66
Papers (1)
  • Functional signatures of the gut microbiome in middle-aged regular runners: insights from a metagenomic study. 2026 PMID 42500599 PMC13395746 own_data
Details
Archive description

Shotgun metagenomic comparison of gut microbiota between runners and controls, focusing on taxonomy, metabolic pathways, antibiotic resistance, and virulence factors.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Signatures of the Gut Microbiome in Middle-Aged”
  • body site study.description · “metagenomic comparison of gut microbiota between runners”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN57421733countryCNR10.90sample.attr.geo_loc_nameChina: Jingmen
SAMN57421733latitude31.0400R10.90biosample.attribute:lat_lon31.04 N 112.20 E
SAMN57421733location_localityJingmenR10.85biosample.attribute:geo_loc_nameChina: Jingmen
SAMN57421733longitude112.2000R10.90biosample.attribute:lat_lon31.04 N 112.20 E
Sequencing

66 runs over 66 samples · mean 11.07 Gbp per run (median 10.72 Gbp, total 730.84 Gbp; 66 runs with a base count) · layout PAIRED 66 · platform ILLUMINA 66 · models Illumina NovaSeq 6000 (66) · 0% of runs with a Sandpiper profile · first public 2026-05-02

Authors (12)

Ai X first · Liu R · Lv Y · Chen L · Duan R · Ma X · Li L · Ding H · Shen H · Hu Y · Zhu X · Zhang Y last

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1457655.csv.gz (2.3 KB) · parquet (71.8 KB) — all 66 samples, every field with route and confidence · PRJNA1457655_determinations.csv.gz (1.7 KB) — 264 evidence rows

Samples (66 · every field this project has values for · hover a cell for its source)
Loading the sample table…