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PRJNA1469299 SRP703367

Adolescent depression gut microbiome across China regions

Geographic Heterogeneity of Gut Microbiome Disturbances in Adolescent Depression: A Metagenomic Analysis

72 samples from adolescents with major depressive disorder across Chongqing, Xizang, and Hubei, China; cross-sectional metagenomic study of gut microbiome differences between regions. machine-written summary

72 samples · 72 runs · CN · Child · 2026 · 13.72 Gbp / sample

Sources
✓Sequence archive 288–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive288 sample values (country, latitude, location locality, longitude)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adolescent72
Country
CN72
Body site
primary72
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 70 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)this project, 30–100 Gbp: 2 samplesall projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 13.72 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category72 100%
country72 100%72
health_condition0 0%
subject_id0 0%
detailed_location72 100%
latitude72 100%72
location_locality72 100%72
longitude72 100%72
Details
Archive description

This multi-center study investigated gut microbiome alterations in adolescents with major depressive disorder (MDD) across three distinct regions in China: Chongqing, Xizang, and Hubei.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adolescent and child by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_child_over_36m”
  • body site study.title · “Geographic Heterogeneity of Gut Microbiome Disturbances in”
  • body site study.description · “multi-center study investigated gut microbiome alterations in”
  • life stage study.title · “Microbiome Disturbances in Adolescent Depression: A Metagenomic”
  • life stage study.description · “microbiome alterations in adolescents with major depressive”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_child_over_36m”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN57384578countryCNR10.90sample.attr.geo_loc_nameChina: Wuhan
SAMN57384578latitude30.5900R10.90biosample.attribute:lat_lon30.59 N 114.30 E
SAMN57384578location_localityWuhanR10.85biosample.attribute:geo_loc_nameChina: Wuhan
SAMN57384578longitude114.3000R10.90biosample.attribute:lat_lon30.59 N 114.30 E
Sequencing

72 runs over 72 samples · mean 15.50 Gbp per run (median 13.72 Gbp, total 1,116.14 Gbp; 72 runs with a base count) · layout PAIRED 72 · platform ILLUMINA 72 · models Illumina NovaSeq 6000 (72) · 0% of runs with a Sandpiper profile · first public 2026-05-31

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA1469299.csv.gz (2.5 KB) · parquet (72.0 KB) — all 72 samples, every field with route and confidence · PRJNA1469299_determinations.csv.gz (1.8 KB) — 288 evidence rows

Samples (72 · every field this project has values for · hover a cell for its source)
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