Gut microbiome in type 2 diabetes, herbal vs metformin trial
74 stool samples from adults with type 2 diabetes mellitus, collected at baseline and 24 weeks post-intervention across three randomized groups (Mustadi Ghana Vati, Varadi Ghana Vati, and metformin drug therapy). machine-written summary
74 samples · 74 runs · IN · Adult · 2026 · 0.22 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 514 sample values (collection date, country, intervention, location locality, location region, subject id, timepoint) |
| ✓ Abstract / description | 148 sample values (health condition, health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Non-antibiotic pharmaceutical given as the study intervention (metformin design randomized_controlled_trial · population type2_diabetes · Mustadi Ghana Vati, Varadi Ghana Vati (herbal formulations) or Metformin
“randomized into 3 groups with interventions” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal
37 of 37 people sampled more than once (74 samples; median 2, up to 2 per person) · follow-up median 6 mo (max 7 mo) · median interval between samples 6 mo (time from collection dates). Schedule stated by the source: “stool at baseline and 24 weeks after intervention” (time origin: intervention_start); stated follow-up 6 mo.
Each row is one person (35 shown of 37); dots are samples at days since that person's first sample.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 74 | 100% | ||||
| country | 74 | 100% | 74 | |||
| health_condition | 74 | 100% | 74 | |||
| subject_id | 74 | 100% | 74 | |||
| detailed_location | 74 | 100% | ||||
| health_condition_detail | 74 | 100% | 74 | |||
| intervention | 74 | 100% | 74 | |||
| location_locality | 74 | 100% | 74 | |||
| location_region | 74 | 100% | 74 | |||
| timepoint_label | 74 | 100% | 74 | |||
| collection_date | 70 | 95% | 70 |
Archive description
Gut microbiome analysis done on 37 patients with recently diagnosed Type 2 diabetes mellitus were randomized into 3 groups with interventions such as Group A Mustadi Ghana Vati, Group B Varadi Ghana Vati and Group C Metformin. The stool sample for Gut Microbiome were collected during baseline and 24 weeks after the intervention and analysed
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Changes in the Gut Microbiome Following Mustadi”
- body site study.description · “Gut microbiome analysis done”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN60398958 | collection_date | 2024-11-19 | R1 | 0.90 | biosample.attribute:collection_date | 2024-11-19 |
| SAMN60398958 | country | IN | R1 | 0.90 | sample.attr.geo_loc_name | India: Bengaluru, Karnataka |
| SAMN60398958 | health_condition | type2_diabetes | R4 | 0.50 | study.description | recently diagnosed Type 2 diabetes mellitus |
| SAMN60398958 | health_condition_detail | recently diagnosed Type 2 diabetes mellitus | R4 | 0.50 | study.description | recently diagnosed Type 2 diabetes mellitus |
| SAMN60398958 | intervention | drug_therapy | R1 | 0.70 | sample.name_rule:source_material_id | source_material_id: DM01209_Metformin_Baseline |
| SAMN60398958 | location_locality | Bengaluru | R1 | 0.85 | biosample.attribute:geo_loc_name | India: Bengaluru, Karnataka |
| SAMN60398958 | location_region | Karnataka | R1 | 0.85 | biosample.attribute:geo_loc_name | India: Bengaluru, Karnataka |
| SAMN60398958 | subject_id | 01209 | R1 | 0.70 | sample.name_rule:source_material_id | source_material_id: DM01209_Metformin_Baseline |
| SAMN60398958 | timepoint_label | Baseline | R1 | 0.70 | sample.name_rule:source_material_id | source_material_id: DM01209_Metformin_Baseline |
Sequencing
74 runs over 74 samples · mean 0.25 Gbp per run (median 0.22 Gbp, total 18.29 Gbp; 74 runs with a base count) · layout SINGLE 74 · platform OXFORD_NANOPORE 74 · models PromethION (74) · 0% of runs with a Sandpiper profile · first public 2026-05-27
Authors (0)
No author record.
Downloads
PRJNA1470177.csv.gz (3.1 KB) · parquet (74.4 KB) — all 74 samples, every field with route and confidence · PRJNA1470177_determinations.csv.gz (6.0 KB) — 662 evidence rows