Stool metagenomes in children with ALL during chemotherapy
873 longitudinal stool samples from children with acute lymphoblastic leukemia, collected at diagnosis, end of induction, and ~6 months later during chemotherapy, within a dietary counseling study. machine-written summary
873 samples · 873 runs · US · Child · 2026 · 0.18 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 5,238 sample values (country, latitude, location region, longitude, subject id, timepoint) |
| ✓ Abstract / description | 1,746 sample values (health condition, health condition detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Other administered intervention (see intervention_detail) design observational_with_procedure · population other_cancer · Prospective dietary counseling study during chemotherapy, samples longitudinal
“prospective dietary counseling study” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
82 of 82 people sampled more than once (873 samples; median 12, up to 21 per person). Schedule stated by the source: “stool at diagnosis, end of induction, and approximately six months after diagnosis” (time origin: diagnosis); stated follow-up 6 mo.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 873 | 100% | ||||
| country | 873 | 100% | 873 | |||
| health_condition | 873 | 100% | 873 | |||
| subject_id | 873 | 100% | 873 | |||
| detailed_location | 873 | 100% | ||||
| health_condition_detail | 873 | 100% | 873 | |||
| latitude | 873 | 100% | 873 | |||
| location_region | 873 | 100% | 873 | |||
| longitude | 873 | 100% | 873 | |||
| timepoint_label | 873 | 100% | 873 |
Archive description
Shotgun metagenomic sequencing was performed on serial stool samples collected from children with acute lymphoblastic leukemia during the first six months of chemotherapy. Samples were obtained at diagnosis, end of induction, and approximately six months after diagnosis to characterize longitudinal changes in microbial taxonomic composition and functional potential. The dataset includes de-identified samples collected within a prospective dietary counseling study.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler and child by opus_adjudicated with confidence 0.60. Assay shotgun_dna.
- host study.description · “children with acute lymphoblastic leukemia”
- body site study.title · “Longitudinal stool metagenomes”
- life stage study.title · “from children with acute lymphoblastic leukemia”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN62222162 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA:NY |
| SAMN62222162 | health_condition | other_disease | R4 | 0.50 | study.description | children with acute lymphoblastic leukemia |
| SAMN62222162 | health_condition_detail | Acute lymphoblastic leukemia during chemotherapy | R4 | 0.50 | study.description | children with acute lymphoblastic leukemia |
| SAMN62222162 | latitude | 40.8075 | R1 | 0.90 | biosample.attribute:lat_lon | 40.8075 N 73.9626 W |
| SAMN62222162 | location_region | New York | R1 | 0.75 | biosample.attribute:geo_loc_name | USA:NY |
| SAMN62222162 | longitude | -73.9626 | R1 | 0.90 | biosample.attribute:lat_lon | 40.8075 N 73.9626 W |
| SAMN62222162 | subject_id | 97900101 | R1 | 0.70 | sample.name_rule:library_names | 97900101A_20200124_L1 |
| SAMN62222426 | subject_id | 97900218 | R1 | 0.70 | sample.name_rule:library_name | 97900218A_20200124_L1 |
| SAMN62222162 | timepoint_label | A | R1 | 0.70 | sample.name_rule:library_names | 97900101A_20200124_L1 |
| SAMN62222430 | timepoint_label | A | R1 | 0.70 | sample.name_rule:library_name | 97900218A_FOBT_L1 |
Sequencing
873 runs over 873 samples · mean 0.21 Gbp per run (median 0.18 Gbp, total 184.83 Gbp; 873 runs with a base count) · layout PAIRED 493, SINGLE 380 · platform ILLUMINA 873 · models NextSeq 550 (873) · 0% of runs with a Sandpiper profile · first public 2026-08-07 – 2026-08-08
Authors (0)
No author record.
Downloads
PRJNA1508239.csv.gz (17.4 KB) · parquet (96.2 KB) — all 873 samples, every field with route and confidence · PRJNA1508239_determinations.csv.gz (42.4 KB) — 6,984 evidence rows