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PRJNA1513446 SRP727432

Meconium microbiota in fetal growth restriction neonates

Metagenomic sequencing of meconium microbiota of neonates

44 meconium samples from neonates, case-control design comparing fetal growth restriction (24 samples) with healthy controls (20 samples). machine-written summary

44 samples · 44 runs · CN · Infant / toddler · 2026 · 5.38 Gbp / sample

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Sources

✓Sequence archive 352○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave

✓ Sequence archive	352 sample values (age, collection date, country, family id, family role, health condition, health condition detail, subject id)
○ Abstract / description	read; no usable statement
– Full text	no open-access full text linked
– Supplementary tables	no supplementary tables available (or none open access)
– External resources	not covered by the external resources we ingest
– User contribution	nothing uploaded yet
– Human verified	not yet checked by a person · I checked this project — verify it

Samples at a glance

1 country

Age

neonate44

Condition

other_disease24

healthy_control20

Country

CN44

Body site

primary44

Sequencing depth per sample · this project all projects

Sampling design and relatedness

twins

22 twin pairs (larger/smaller twin, selective FGR-discordant), one meconium sample each; zygosity not given · 22 families with 44 sampled people, 44 twin sets.

22 × twin×2

twin · circles are people (pale = no sequenced sample), arrows run donor → recipient and parent → child, curved lines join twins, partners and siblings, squares are shared settings or families without recorded roles. Shown: 22 linked groups from explicit relations. 44 people in the project overall.

Families (22)

family	members	samples
MCC-01	twin×2	SAMN62449981 · SAMN62449982
MCC-02	twin×2	SAMN62449983 · SAMN62449984
MCE-11	twin×2	SAMN62450021 · SAMN62450022
MCE-10	twin×2	SAMN62450019 · SAMN62450020
MCE-09	twin×2	SAMN62450017 · SAMN62450018
MCE-08	twin×2	SAMN62450015 · SAMN62450016
MCE-07	twin×2	SAMN62450013 · SAMN62450014
MCE-06	twin×2	SAMN62450011 · SAMN62450012
MCE-05	twin×2	SAMN62450009 · SAMN62450010
MCE-04	twin×2	SAMN62450007 · SAMN62450008
MCE-03	twin×2	SAMN62450005 · SAMN62450006
MCE-02	twin×2	SAMN62450003 · SAMN62450004
MCE-01	twin×2	SAMN62450001 · SAMN62450002
MCC-10	twin×2	SAMN62449999 · SAMN62450000
MCC-09	twin×2	SAMN62449997 · SAMN62449998
MCC-08	twin×2	SAMN62449995 · SAMN62449996
MCC-07	twin×2	SAMN62449993 · SAMN62449994
MCC-06	twin×2	SAMN62449991 · SAMN62449992
MCC-05	twin×2	SAMN62449989 · SAMN62449990
MCC-04	twin×2	SAMN62449987 · SAMN62449988
MCC-03	twin×2	SAMN62449985 · SAMN62449986
MCE-12	twin×2	SAMN62450023 · SAMN62450024

How longitudinal and relatedness information is derived

Community composition

No Sandpiper profile for this project's samples yet.

Field coverage

field	samples	coverage	R1
age_category	44	100%
country	44	100%	44
health_condition	44	100%	44
subject_id	44	100%	44
age_at_collection_days	44	100%	44
collection_date	44	100%	44
family_id	44	100%	44
family_role	44	100%	44
health_condition_detail	44	100%	44

Details

Archive description

Neonatal gut dysbiosis of Fetal Growth Restriction

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of neonate and infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

host external_curation.infant_catalog · “infant triage verdict include”
body site study.title · “Metagenomic sequencing of meconium microbiota of neonates”
body site study.description · “Neonatal gut dysbiosis of Fetal”
life stage study.title · “Metagenomic sequencing of meconium microbiota of neonates”
life stage study.description · “Neonatal gut dysbiosis of”
life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”

Evidence examples (one per field × route)

sample	field	value	route	conf.	source	quote
SAMN62449981	age_at_collection_days	1	R1	0.90	biosample_attr	1 day
SAMN62449981	collection_date	2018	R1	0.85	biosample.attribute:collection_date	2018
SAMN62449981	country	CN	R1	0.90	biosample_attr	China: BeiJing
SAMN62449981	family_id	MCC-01	R1	0.70	biosample.attribute:host_subject_id	MCC-01L
SAMN62449981	family_role	twin	R1	0.85	biosample.attribute:fetal_size_group	larger twin
SAMN62449981	health_condition	healthy_control	R1	0.80	sample.attr.host_disease	host_disease=none, larger twin
SAMN62449981	health_condition_detail	none, larger twin	R1	0.90	biosample.attribute:host_disease	host_disease: none, larger twin
SAMN62449981	subject_id	MCC-01L	R1	0.85	biosample_attr	MCC-01L

Sequencing

44 runs over 44 samples · mean 4.72 Gbp per run (median 5.38 Gbp, total 207.49 Gbp; 44 runs with a base count) · layout PAIRED 44 · platform ILLUMINA 44 · models Illumina NovaSeq 6000 (44) · 0% of runs with a Sandpiper profile · first public 2026-08-28

Authors (0)

No author record.

Downloads

PRJNA1513446.csv.gz (2.3 KB) · parquet (72.0 KB) — all 44 samples, every field with route and confidence · PRJNA1513446_determinations.csv.gz (3.4 KB) — 352 evidence rows

Samples (44 · every field this project has values for · hover a cell for its source)

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