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PRJNA1522603 SRP733228

Pathogen co-infection in BALF, renal transplant pneumonia

Pathogen co-infection in bronchoalveolar lavage fluid of post-renal transplant pneumonia patients and its correlations with patient physiological indicators

Single-center case-control metagenomic study of 188 bronchoalveolar lavage fluid samples from renal transplant recipients with pneumonia, analyzing pathogen co-infection and correlations with clinical indicators. machine-written summary

188 samples · 188 runs · CN · Age unknown · 2026 · 1.05 Gbp / sample

Sources
✓Sequence archive 940✓Abstract / description 376–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive940 sample values (collection date, country, latitude, location locality, longitude)
✓ Abstract / description376 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown188
Condition
transplant_or_immunocompromised188
Country
CN188
Body site
primary188
Collected 2020–2023
2020: 62 samples2021: 63 samples2022: 9 samples2023: 54 samples20202023
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 15 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 31 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 33 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 109 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.05 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country188 100%188
health_condition188 100%188
subject_id0 0%
collection_date188 100%188
detailed_location188 100%
health_condition_detail188 100%188
latitude188 100%188
location_locality188 100%188
longitude188 100%188
Details
Archive description

To analyze the co-infection of pathogenic microorganisms in bronchoalveolar lavage fluid of patients with pneumonia following renal transplantation and examine the correlation between these pathogens and patients physico-chemical indicators, we conducted a single center retrospective analysis of metagenomic data and clinical information from the BALF of 221 patients who developed pneumonia after renal transplantation.

How this project entered the registry

Classified as human lower respiratory / gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host study.title · “post-renal transplant pneumonia patients”
  • body site study.title · “bronchoalveolar lavage fluid”
  • body site study.description · “bronchoalveolar lavage fluid of patients with pneumonia”
  • body site sample.attr.env_medium · “feces (n=188/188)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN62900851collection_date2021-05-16R10.90biosample.attribute:collection_date2021-05-16
SAMN62900851countryCNR10.90sample.attr.geo_loc_nameChina: Guangzhou
SAMN62900851health_conditiontransplant_or_immunocompromisedR40.50study.descriptionpneumonia following renal transplantation
SAMN62900851health_condition_detailpost-renal transplant pneumoniaR40.50study.descriptionpneumonia following renal transplantation
SAMN62900851latitude22.9500R10.90biosample.attribute:lat_lon22.950001 N 113.500001 E
SAMN62900851location_localityGuangzhouR10.85biosample.attribute:geo_loc_nameChina: Guangzhou
SAMN62900851longitude113.5000R10.90biosample.attribute:lat_lon22.950001 N 113.500001 E
Sequencing

188 runs over 188 samples · mean 0.95 Gbp per run (median 1.05 Gbp, total 179.11 Gbp; 188 runs with a base count) · layout PAIRED 188 · platform ILLUMINA 188 · models Illumina HiSeq 3000 (188) · 0% of runs with a Sandpiper profile · first public 2026-09-05

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA1522603.csv.gz (5.5 KB) · parquet (78.0 KB) — all 188 samples, every field with route and confidence · PRJNA1522603_determinations.csv.gz (11.2 KB) — 1,316 evidence rows

Samples (188 · every field this project has values for · hover a cell for its source)
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